Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.56 |
| ▸ | NPC1 | O15118 | 8/20 | 0.56 |
| ▸ | GAA | P10253 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25830149 | 1.00 | RAB9A (0.56) | RAB9ANPC1GAAMAPTSMN1; SMN2 | |
| SCHEMBL12726207 | 1.00 | RAB9A (0.56) | RAB9ANPC1GAAMAPTSMN1; SMN2 | |
| SCHEMBL24870922 | 0.80 | RAB9A (0.56) | RAB9ANPC1GAAMAPTSMN1; SMN2 | |
| SCHEMBL29033677 | 0.79 | RAB9A (0.51) | RAB9ANPC1GAAMAPTSMN1; SMN2 | |
| SCHEMBL25234452 | 0.79 | RAB9A (0.56) | RAB9ANPC1GAAMAPTSMN1; SMN2 | |
| SCHEMBL8342118 | 0.77 | PAX8 (0.65) | RAB9ANPC1GAAMAPTSMN1; SMN2 | |
| SCHEMBL7522459 | 0.77 | RAB9A (0.76) | RAB9ANPC1GAAMAPTSMN1; SMN2 | |
| SCHEMBL3114363 | 0.77 | RAB9A (0.53) | RAB9ANPC1GAAMAPTSMN1; SMN2 | |
| SCHEMBL3114355 | 0.77 | RAB9A (0.53) | RAB9ANPC1GAAMAPTSMN1; SMN2 | |
| SCHEMBL5051613 | 0.77 | PAX8 (0.65) | RAB9ANPC1GAAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9891237-B2 | Fluorescent sensor for metal cation detection based on 2-(2′-hydroxyphenyl)benzazole containing a Schiff base moiety | THE UNIVERSITY OF AKRON (US) | 2018-02-13 | — | — | US | disclosed |
| US-9891237-B2 | Fluorescent sensor for metal cation detection based on 2-(2′-hydroxyphenyl)benzazole containing a Schiff base moiety | THE UNIVERSITY OF AKRON (US) | 2018-02-13 | — | — | US | disclosed |
| US-20150031067-A1 | NOVEL FLUORESCENT SENSOR FOR METAL CATION DETECTION BASED ON 2-(2'-HYDROXYPHENYL)BENZAZOLE CONTAINING A SCHIFF BASE MOIETY | THE UNIVERSITY OF AKRON | 2015-01-29 | — | — | US | disclosed |
| US-20150031067-A1 | NOVEL FLUORESCENT SENSOR FOR METAL CATION DETECTION BASED ON 2-(2'-HYDROXYPHENYL)BENZAZOLE CONTAINING A SCHIFF BASE MOIETY | THE UNIVERSITY OF AKRON | 2015-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150031067-A1 | NOVEL FLUORESCENT SENSOR FOR METAL CATION DETECTION BASED ON 2-(2'-HYDROXYPHENYL)BENZAZOLE CONTAINING A SCHIFF BASE MOIETY | CNBP, CA2, HELZ | RAB9A 4307/4885NPC1 2915/4885GAA 659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.