Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.47 |
| ▸ | NPC1 | O15118 | 10/20 | 0.47 |
| ▸ | GAA | P10253 | 10/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18627145 | 0.80 | RAB9A (0.45) | RAB9ANPC1GAASMN1; SMN2MEN1 | |
| SCHEMBL1144420 | 0.73 | RAB9A (0.49) | RAB9ANPC1GAASMN1; SMN2MEN1 | |
| SCHEMBL1144419 | 0.73 | RAB9A (0.49) | RAB9ANPC1GAASMN1; SMN2MEN1 | |
| SCHEMBL25234452 | 0.72 | RAB9A (0.56) | RAB9ANPC1GAASMN1; SMN2MEN1 | |
| SCHEMBL18528347 | 0.71 | RAB9A (0.51) | RAB9ANPC1GAASMN1; SMN2MEN1 | |
| SCHEMBL17234471 | 0.71 | RAB9A (0.51) | RAB9ANPC1GAASMN1; SMN2MEN1 | |
| SCHEMBL25830149 | 0.70 | RAB9A (0.56) | RAB9ANPC1GAASMN1; SMN2MEN1 | |
| SCHEMBL16418407 | 0.70 | RAB9A (0.56) | RAB9ANPC1GAASMN1; SMN2MEN1 | |
| SCHEMBL12726207 | 0.70 | RAB9A (0.56) | RAB9ANPC1GAASMN1; SMN2MEN1 | |
| SCHEMBL7831620 | 0.69 | RAB9A (0.51) | RAB9ANPC1GAASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539543-A1 | PYRIDYL HYDRAZONES FOR THE TREATMENT OF TUBERCULOSIS AND RELATED DISEASES | TECNIMEDE SOCIEDADE TECNICO-MEDICINAL S.A. (PT) | 2019-09-18 | — | — | EP | disclosed |