SCHEMBL18627697

SCHEMBL18627697

CN(C)c1ccc2c3ccccc3n(-c3ccccc3)c2c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.60
ATM Q13315 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
PRMT5 O14744 2/20 0.42
MAT2A P31153 2/20 0.42
ALDH1A1 P00352 4/20 0.41
GFER P55789 1/20 0.41
REN P00797 1/20 0.39
MAPT P10636 3/20 0.39
HPGD P15428 2/20 0.39
HSD17B10 Q99714 2/20 0.39
MAPK8 P45983 1/20 0.39
THRB P10828 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HTR6 P50406 1/20 0.38
PMM2 O15305 1/20 0.38
MPI P34949 1/20 0.38
PHOSPHO1 Q8TCT1 1/20 0.38
PGR P06401 2/20 0.38
KDR P35968 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25794648 0.90 KDM4E (0.60) KDM4EATML3MBTL1PRMT5MAT2A
SCHEMBL18745246 0.89 KDM4E (0.58) KDM4EATML3MBTL1PRMT5MAT2A
SCHEMBL22857674 0.87 KDM4E (0.56) KDM4EATML3MBTL1PRMT5MAT2A
SCHEMBL18564739 0.87 KDM4E (0.56) KDM4EATML3MBTL1PRMT5MAT2A
SCHEMBL18565069 0.86 KDM4E (0.55) KDM4EATML3MBTL1PRMT5MAT2A
SCHEMBL24729779 0.85 KDM4E (0.62) KDM4EATML3MBTL1MAT2AALDH1A1
SCHEMBL25800613 0.84 KDM4E (0.53) KDM4EATML3MBTL1PRMT5MAT2A
SCHEMBL25793423 0.84 KDM4E (0.53) KDM4EATML3MBTL1PRMT5MAT2A
SCHEMBL9912993 0.84 ALDH1A1 (0.53) KDM4EATML3MBTL1ALDH1A1GFER
SCHEMBL7100405 0.84 KDM4E (0.59) KDM4EATML3MBTL1ALDH1A1GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212135-A1 LIGHT EMITTING ELEMENT, AMINE COMPOUND FOR THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-06 US disclosed
US-9905772-B2 Material for organic electroluminescence device and use thereof LUMINESCENCE TECHNOLOGY CORP. (TW) 2018-02-27 US disclosed
US-20170077410-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND USE THEREOF LUMINESCENCE TECHNOLOGY CORP. (TW) 2017-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212135-A1 LIGHT EMITTING ELEMENT, AMINE COMPOUND FOR THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME SLC1A2, SLC18A2, SLC18A1 KDM4E 1468/4885ATM 2881/4885L3MBTL1 1920/4885
US-20170077410-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND USE THEREOF HBS1L, EML4, EBPL KDM4E 1969/4885ATM 4318/4885L3MBTL1 307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.