Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 6/20 | 0.55 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL10592361 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL7997152 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL7780283 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL8713351 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL1585944 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL17309672 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL11469243 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL8430973 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL2970314 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL11309619 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3495 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466799-B | N-substituted phthalic acid diamide preparation method of imine compound | 西北师范大学 | 2024-12-24 | — | — | CN | claimed |
| CN-118342829-A | Low-temperature heat-sealing type single polyethylene composite packaging film and preparation method thereof | 广东中兴塑料纸类印刷有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-117568623-B | Process for extracting lithium-containing polymetallic brine from lithium ore without waste tailings by wet smelting | 徐浩 | 2024-07-12 | — | — | CN | claimed |
| CN-118326559-A | Antioxidant yarn for jet vortex spinning and preparation method thereof | 江苏利华纺织有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-117210066-B | Chitin zwitterionic antifouling coating, preparation method and application thereof | 天津永续新材料有限公司 | 2024-07-05 | — | — | CN | claimed |
| EP-4384142-A1 | MORDANT-FREE HAIR DYE CONTAINING PLANT DYES | Henkel AG & Co. KGaA (DE) | 2024-06-19 | — | — | EP | claimed |
| CN-115814157-B | Antibacterial coating for osseointegration material and preparation method thereof | 齐鲁工业大学 | 2024-06-07 | — | — | CN | claimed |
| CN-115684428-B | Method for non-targeted qualitative detection of bisphenol substances based on dansyl chloride derivative combined with in-mass spectrum source cleavage | 暨南大学 | 2024-06-07 | — | — | CN | claimed |
| CN-115873438-B | Solvent corrosion resistant coating material for precision instrument and preparation method thereof | 齐鲁工业大学 | 2024-06-04 | — | — | CN | claimed |
| CN-115873502-B | Weather-resistant outdoor building material surface coating and preparation method thereof | 齐鲁工业大学 | 2024-06-04 | — | — | CN | claimed |
| EP-0491936-A1 | VERY RAPID DETECTION OF FUNGAL INFECTIONS. | DIAGNOSTIC MARKERS INC (US) | 1992-07-01 | — | — | EP | claimed |
| US-5098830-A | VERY RAPID DETECTION OF FUNGAL INFECTIONS | DIAGNOSTIC MARKERS, INC. (US) | 1992-03-24 | — | — | US | claimed |
| WO-1992001373-A1 | VERY RAPID DETECTION OF FUNGAL INFECTIONS | DIAGNOSTIC MARKERS, INC. (US) | 1992-02-06 | — | — | WO | claimed |
| US-5073502-A | Method and apparatus for analyzing total organic halogens | UNITED TECHNOLOGIES CORPORATION (US) | 1991-12-17 | — | — | US | claimed |
| US-5011824-A | Rectal motilin preparation | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-04-30 | — | — | US | claimed |
| EP-0369437-A2 | Motilin preparation | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-05-23 | — | — | EP | claimed |
| US-4756837-A | Treating black liquor with sodium or potassium hydroxide or carbonate, heating, pressurization, oxidation | DOMTAR INC. (CA) | 1988-07-12 | — | — | US | claimed |
| US-4539380-A | INORGANIC SALTS AS EMULSIFIERS | FORMOSA PLASTICS CORPORATION (TW) | 1985-09-03 | — | — | US | claimed |
| US-4425313-A | POTASSIUM CARBONATE AND BICARBONAJTE | COOPER HAL B H | 1984-01-10 | — | — | US | claimed |
| US-4096037-A | QUANTITATIVE ANALYSIS, SERUMS | PITMAN-MOORE, INC. (US) | 1978-06-20 | — | — | US | claimed |