Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 2/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 7/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.31 |
| ▸ | DNASE1 | P24855 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18628183 | 0.87 | TGFBR1 (0.33) | TGFBR1ACVR1GRM5 | |
| Hydrochloric Acid SCHEMBL18628211 | 0.85 | KCNH2 (0.37) | TGFBR1ACVR1 | |
| SCHEMBL14745807 | 0.85 | IP6K1 (0.35) | TGFBR1ACVR1HSD17B10MAPTL3MBTL1 | |
| SCHEMBL18628171 | 0.83 | HSD17B10 (0.34) | HSD17B10MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL18628146 | 0.83 | HSD17B10 (0.34) | HSD17B10MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL18628139 | 0.81 | HSD17B10 (0.33) | HSD17B10MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL18628178 | 0.81 | ROCK2 (0.33) | GRM5MEN1KMT2AMAOAMAOB | |
| SCHEMBL18628175 | 0.81 | KIF11 (0.35) | HSD17B10MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL18628247 | 0.80 | KIF11 (0.32) | HSD17B10MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL18628197 | 0.80 | HSD17B10 (0.37) | HSD17B10MAPTL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2750678-B1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC THERAPEUTICS INC (US) | 2017-03-22 | — | — | EP | claimed |