SCHEMBL186285

SCHEMBL186285

COCCOC(=O)c1ccccc1C(=O)OCCOC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 1.00
ALDH1A1 P00352 10/20 0.68
TDP1 Q9NUW8 4/20 0.63
L3MBTL1 Q9Y468 3/20 0.63
CYP3A4 P08684 4/20 0.61
MAPK1 P28482 3/20 0.61
TP53 P04637 2/20 0.61
LMNA P02545 2/20 0.59
HSD17B10 Q99714 5/20 0.50
NPC1 O15118 3/20 0.50
HPGD P15428 2/20 0.50
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
GLA P06280 1/20 0.50
HIF1A Q16665 1/20 0.50
KDM4E B2RXH2 2/20 0.49
MEN1 O00255 1/20 0.49
NFKB1 P19838 1/20 0.49
NFKB2 Q00653 1/20 0.49
KMT2A Q03164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29389335 1.00 TSHR (1.00) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL12377229 0.94 TSHR (0.89) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL2809758 0.94 TSHR (0.89) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL5599951 0.94 TSHR (0.89) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL186286 0.93 TSHR (0.86) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL8900471 0.89 TSHR (0.80) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL11530630 0.89 TSHR (0.79) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL14409194 0.89 TSHR (0.79) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL9581141 0.88 TSHR (0.79) TSHRALDH1A1TDP1L3MBTL1CYP3A4
Diethyl Phthalate SCHEMBL5492207 0.88 TSHR (0.81) TSHRALDH1A1TDP1L3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 773 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4619462-A1 METHOD FOR THE EXTRACTION AND TRANSFORMATION, BY ALCOHOLYSIS AND HYDROLYSIS, OF PHTHALATES CONTAINED IN PVC PLASTICS IFP Energies nouvelles (FR) 2025-09-24 EP claimed
EP-4619461-A1 METHOD FOR EXTRACTION AND TRANSFORMATION BY HYDROLYSIS OF PHTHALATES CONTAINED IN PVC PLASTICS IFP Energies nouvelles (FR) 2025-09-24 EP claimed
CN-112639458-B Mass spectrometer, and evaluation and correction method, analysis method, and reagent therefor 株式会社岛津制作所 2025-05-27 CN claimed
CN-120032748-A Method for deducing phthalate long-term water quality standard 安徽工程大学 2025-05-23 CN claimed
US-12270796-B2 Detection method, analysis method, analysis device and non-transitory computer readable medium SHIMADZU CORPORATION (JP) 2025-04-08 US claimed
CN-119780311-A Method for simultaneously detecting 16 phthalate plasticizers and application thereof 上海微谱检测科技集团股份有限公司 2025-04-08 CN claimed
US-12266517-B2 Method for evaluating mass spectrometry device, method for calibrating mass spectrometry device, analysis method, mass spectrometry device, and mass spectrometry reagent SHIMADZU CORPORATION (JP) 2025-04-01 US claimed
CN-118362657-A Method for measuring various endocrine disruptors in water body 国家地质实验测试中心 2024-07-19 CN claimed
US-20240239983-A1 METHOD FOR EXTRACTION AND TRANSFORMATION BY TRANSESTERIFICATION OF PHTHALATES CONTAINED IN PVC PLASTICS MATERIALS IFP Energies Nouvelles (FR) 2024-07-18 US claimed
US-20240227246-A1 METHOD FOR EXTRACTION AND TRANSFORMATION OF PHTHALATES CONTAINED IN PVC PLASTICS BY MEANS OF ALCOHOL IFP Energies Nouvelles (FR) 2024-07-11 US claimed
US-5104450-A Films, molding materials; fireproof, plasticizing, stabilization, dimensional stability EASTMAN KODAK COMPANY (US) 1992-04-14 US claimed
WO-1992005219-A1 FORMULATIONS OF CELLULOSE ESTERS WITH ARYLENE-BIS(DIARYL PHOSPHATE)S EASTMAN KODAK COMPANY (US) 1992-04-02 WO claimed
EP-0468729-A1 Lubrication of vapour compression heat transfer systems CASTROL LIMITED (GB) 1992-01-29 EP claimed
US-5052415-A Homogeneity coating B.A.T. CIGARETTENFABRIKEN GMBH (DE) 1991-10-01 US claimed
CN-1053073-A Process for the preparation of filled heat-curable compounds of the polyurethane type and compounds obtained OMYA SA (FR) 1991-07-17 CN claimed
EP-0134455-B2 USE OF THERMOPLASTIC POLYURETHANES CONTAINING PLASTICIZERS FOR THE MANUFACTURE OF FOILS AND MOULDED ARTICLES BASF Aktiengesellschaft (DE) 1991-06-26 EP claimed
EP-0134455-B1 USE OF THERMOPLASTIC POLYURETHANES CONTAINING PLASTICIZERS FOR THE MANUFACTURE OF FOILS AND MOULDED ARTICLES BASF Aktiengesellschaft (DE) 1988-03-23 EP claimed
US-4507256-A Process for foaming cellulose acetate rod EASTMAN KODAK COMPANY (US) 1985-03-26 US claimed
EP-0134455-A1 Use of thermoplastic polyurethanes containing plasticizers for the manufacture of foils and moulded articles BASF Aktiengesellschaft (DE) 1985-03-20 EP claimed
WO-1982000033-A1 FILM-FORMING COMPOSITION AND THE METHOD OF MAKING CELLULOSE ESTER FILM EASTMAN KODAK CO (US) 1982-01-07 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239983-A1 METHOD FOR EXTRACTION AND TRANSFORMATION BY TRANSESTERIFICATION OF PHTHALATES CONTAINED IN PVC PLASTICS MATERIALS DDT, TRRAP, DEK TSHR 2645/4885ALDH1A1 3659/4885TDP1 3256/4885
US-20240227246-A1 METHOD FOR EXTRACTION AND TRANSFORMATION OF PHTHALATES CONTAINED IN PVC PLASTICS BY MEANS OF ALCOHOL ADH1C, ADH5, NCEH1 TSHR 3333/4885ALDH1A1 896/4885TDP1 4591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.