SCHEMBL186286

SCHEMBL186286

COCCOC(=O)c1ccccc1C(=O)O

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.86
ALDH1A1 P00352 9/20 0.59
TDP1 Q9NUW8 4/20 0.56
L3MBTL1 Q9Y468 3/20 0.56
MAPK1 P28482 4/20 0.54
CYP3A4 P08684 4/20 0.54
TP53 P04637 2/20 0.54
LMNA P02545 2/20 0.53
ALOX15 P16050 1/20 0.50
HSD17B10 Q99714 3/20 0.49
NPC1 O15118 3/20 0.49
HPGD P15428 2/20 0.49
RAB9A P51151 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
GLA P06280 1/20 0.49
HIF1A Q16665 1/20 0.49
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31541130 0.95 TSHR (0.77) TSHRALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL1286848 0.95 TSHR (0.77) TSHRALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL29389335 0.93 TSHR (1.00) TSHRALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL186285 0.93 TSHR (1.00) TSHRALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL3302489 0.91 ALDH1A1 (0.69) TSHRALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL5492210 0.90 TSHR (0.70) TSHRALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL9581139 0.90 TSHR (0.69) TSHRALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL28117434 0.90 TSHR (0.69) TSHRALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL28492073 0.89 ALDH1A1 (0.67) TSHRALDH1A1TDP1L3MBTL1MAPK1
Phthalic Acid SCHEMBL31495206 0.89 TSHR (0.64) TSHRALDH1A1TDP1MAPK1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117664947-A Method for rapidly screening phthalate ester environmental hormone in edible oil 武汉食品化妆品检验所 2024-03-08 CN claimed
CN-112903884-B Method for simultaneously detecting phthalate compounds and metabolites thereof and application thereof 中国科学院深圳先进技术研究院 2022-07-12 CN claimed
CN-112903884-A Method for simultaneously detecting phthalate compounds and metabolites thereof and application thereof 中国科学院深圳先进技术研究院 2021-06-04 CN claimed
CN-112639458-A Method for evaluating mass spectrometer, method for calibrating mass spectrometer, analysis method, mass spectrometer, and reagent for mass analysis 株式会社岛津制作所 2021-04-09 CN claimed
WO-2020066009-A1 MASS SPECTROMETRY DEVICE EVALUATION METHOD, MASS SPECTROMETRY DEVICE CALIBRATION METHOD, ANALYSIS METHOD, MASS SPECTROMETRY DEVICE, AND MASS SPECTROMETRY REAGENT 株式会社島津製作所 2020-04-02 WO claimed
US-6143484-A ADDING TO EMULSION CONTAINING SILVER HALIDE PARTICLES SUFFICIENT AMOUNT OF SURFACTANT TO PASSIFY SURFACES OF SILVER HALIDE PARTICLES EASTMAN KODAK COMPANY (US) 2000-11-07 US claimed
EP-0586575-A1 DEGRADABLE CELLULOSE POLYMERS BATTELLE MEMORIAL INSTITUTE (US) 1994-03-16 EP claimed
WO-1992020738-A1 DEGRADABLE CELLULOSE POLYMERS BATTELLE MEMORIAL INSTITUTE (US) 1992-11-26 WO claimed
CN-1053073-A Process for the preparation of filled heat-curable compounds of the polyurethane type and compounds obtained OMYA SA (FR) 1991-07-17 CN claimed
JP-55123602-A None JP disclosed
US-12624482-B2 Nonwoven fabrics comprising polylactic acid and surface-treated calcium carbonate OMYA INTERNATIONAL AG (CH) 2026-05-12 US disclosed
EP-4097283-B1 NONWOVEN FABRICS COMPRISING POLYLACTIC ACID AND SURFACE-TREATED CALCIUM CARBONATE OMYA INT AG (CH) 2025-06-25 EP disclosed
CN-117664947-A Method for rapidly screening phthalate ester environmental hormone in edible oil 武汉食品化妆品检验所 2024-03-08 CN disclosed
CN-117177977-A Bicyclic pyridine derivatives 住友制药株式会社 2023-12-05 CN disclosed
US-4246154-A COMPRISING AN AQUEOUS DISPERSION OF HYDROPHOBIC DYE AND VINYL POLYMER FUJI PHOTO FILM CO., LTD. (JP) 1981-01-20 US disclosed
JP-S55123602-A CURE ACCELERATOR COMPOSITION FOR RESIN MITSUBISHI PETROCHEM CO LTD 1980-09-24 JP disclosed
US-4153592-A HYDROPHOBIC-HYDROPHILIC ADDITION INTERPOLYMER, AMINE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-05-08 US disclosed
US-4119743-A RADIATION CURING, HEAT SEALING EASTMAN KODAK COMPANY (US) 1978-10-10 US disclosed
US-4097440-A PAINTS, ADDITION POLYMERS, PLASTICIZERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1978-06-27 US disclosed
US-4070398-A Laminates useful as packaging materials and method for manufacture thereof EASTMAN KODAK COMPANY (US) 1978-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624482-B2 Nonwoven fabrics comprising polylactic acid and surface-treated calcium carbonate STIM1, CA2, CACNA2D4 TSHR 4718/4885ALDH1A1 4227/4885TDP1 4226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.