SCHEMBL1862889

SCHEMBL1862889

CC(=O)Oc1ccccc1C(=O)OCC(C)C

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.70
TSHR P16473 3/20 0.70
KDM4E B2RXH2 4/20 0.58
HSD17B10 Q99714 3/20 0.58
LMNA P02545 1/20 0.58
CYP1A2 P05177 1/20 0.58
CYP2C9 P11712 1/20 0.58
PTGS2 P35354 5/20 0.56
HPGD P15428 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
ESR1 P03372 1/20 0.56
ITGB3 P05106 1/20 0.56
ITGA2B P08514 1/20 0.56
HMGB1 P09429 1/20 0.56
GGT1 P19440 1/20 0.56
PTGS1 P23219 1/20 0.56
BLM P54132 1/20 0.56
NAPRT Q6XQN6 1/20 0.56
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1283916 0.89 ALDH1A1 (0.72) ALDH1A1TSHRKDM4EHSD17B10LMNA
SCHEMBL28026178 0.86 ALDH1A1 (0.68) ALDH1A1TSHRKDM4EHSD17B10LMNA
SCHEMBL10786068 0.86 ALDH1A1 (0.68) ALDH1A1TSHRKDM4EHSD17B10LMNA
SCHEMBL29008201 0.85 ALDH1A1 (0.66) ALDH1A1TSHRKDM4EHSD17B10LMNA
SCHEMBL13609266 0.85 ALDH1A1 (0.57) ALDH1A1TSHRKDM4EHSD17B10LMNA
SCHEMBL15593496 0.85 PTGS2 (0.55) ALDH1A1TSHRKDM4EHSD17B10LMNA
SCHEMBL5665608 0.85 KDM4E (0.55) ALDH1A1TSHRKDM4EHSD17B10LMNA
SCHEMBL2612522 0.85 PTGS2 (0.70) ALDH1A1TSHRKDM4EHSD17B10LMNA
SCHEMBL16007220 0.84 KDM4E (0.51) ALDH1A1TSHRKDM4EHSD17B10LMNA
SCHEMBL1073248 0.84 ALDH1A1 (0.74) ALDH1A1TSHRKDM4EHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1257920-C Catalyst component for olefinic polymerization and its catalyst CHINA PETROLEUM & CHEMICAL (CN) 2006-05-31 CN claimed
CN-1611515-A Catalyst component for olefinic polymerization and its catalyst CHINA PETROCHEMICAL CO LTD (CN) 2005-05-04 CN claimed
CN-117355546-A Spherical catalyst component for olefin polymerization 格雷斯公司 2024-01-05 CN disclosed
CN-107207657-B Process for preparing spherical polymerization catalyst components for olefin polymerization 格雷斯公司 2020-03-03 CN disclosed
CN-104829757-B A kind of ingredient of solid catalyst of olefin polymerization acid esters compound containing bigcatkin willow and its preparation method and application 中国科学院化学研究所 2018-04-27 CN disclosed
EP-3173072-A1 CONVENIENTLY IMPLANTABLE SUSTAINED RELEASE DRUG COMPOSITIONS Ramscor, Inc. (US) 2017-05-31 EP disclosed
US-20150273066-A1 CONVENIENTLY IMPLANTABLE SUSTAINED RELEASE DRUG COMPOSITIONS RAMSCOR INC (US) 2015-10-01 US disclosed
CN-104829757-A Salicylate-compound-containing solid catalyst component for olefin polymerization, and preparation method and application thereof CHINESE ACAD INST CHEMISTRY 2015-08-12 CN disclosed
US-9011915-B2 Conveniently implantable sustained release drug compositions RAMSCOR, INC. (US) 2015-04-21 US disclosed
CN-103635494-A Method for polymerizing [alpha]-olefin SUNALLOMER LTD 2014-03-12 CN disclosed
EP-2452670-A1 Conveniently implantable sustained release drug compositions Ramscor, Inc. (US) 2012-05-16 EP disclosed
CN-1611515-A Catalyst component for olefinic polymerization and its catalyst CHINA PETROCHEMICAL CO LTD (CN) 2005-05-04 CN disclosed
CN-1054384-C Process for the preparation of olefin polymer MITSUI CHEMICALS CO LTD (JP) 2000-07-12 CN disclosed
EP-0385765-B1 Process for polymerizing olefins and catalyst for polymerizing olefins MITSUI PETROCHEMICAL IND (JP) 1995-05-03 EP disclosed
CN-1090854-A The preparation method of olefin polymer MITSUI PETROCHEMICAL IND (JP) 1994-08-17 CN disclosed
EP-0385765-A2 Process for polymerizing olefins and catalyst for polymerizing olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-09-05 EP disclosed
EP-0086643-B1 CATALYST COMPOSITION AND PROCESS FOR POLYMERIZING OLEFINS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1987-09-09 EP disclosed
EP-0086645-B1 CATALYST COMPOSITION AND PROCESS FOR POLYMERIZING OLEFINS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1986-09-24 EP disclosed
EP-0086645-A2 Catalyst composition and process for polymerizing olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1983-08-24 EP disclosed
EP-0086643-A2 Catalyst composition and process for polymerizing olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1983-08-24 EP disclosed