⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972093 | 0.71 | ADRB2 (0.38) | — | |
| SCHEMBL1897926 | 0.71 | — | — | |
| SCHEMBL15513421 | 0.71 | — | — | |
| SCHEMBL8954165 | 0.64 | — | — | |
| SCHEMBL294096 | 0.63 | — | — | |
| SCHEMBL1407387 | 0.62 | — | — | |
| SCHEMBL8052611 | 0.62 | — | — | |
| SCHEMBL1407388 | 0.62 | — | — | |
| SCHEMBL12226 | 0.62 | — | — | |
| SCHEMBL2957555 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4407 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140990-A1 | PYRAZOLE FUSED RING COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2024-07-04 | — | — | WO | claimed |
| US-20240217969-A1 | SUBSTITUTED PYRROLE CARBOXAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2024-07-04 | — | — | US | claimed |
| EP-4393920-A1 | AROMATIC RING-CONTAINING BIOLOGICAL ANTAGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2024-07-03 | — | — | EP | claimed |
| WO-2024120505-A1 | FUSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, INTERMEDIATES THEREOF, AND USE THEREOF | 上海枢境生物科技有限公司 | 2024-06-13 | — | — | WO | claimed |
| CN-118063484-A | Semi-synthesis method of Caraphenol A | 贵州医科大学 | 2024-05-24 | — | — | CN | claimed |
| CN-118063500-A | Preparation method of (2S, 5S) -5-hydroxy piperidine-2-formic acid | 浙江九洲药业股份有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-117986215-A | 2-Phenyl-4-acyl benzofurans, preparation and application thereof | 中国医学科学院药物研究所 | 2024-05-07 | — | — | CN | claimed |
| EP-4347580-A1 | 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND MEDICAL USES THEREOF | Novartis AG (CH) | 2024-04-10 | — | — | EP | claimed |
| CN-117836294-A | Biological antagonist containing aromatic ring, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-113387954-B | Preparation method of adefovir intermediate | 上海特化医药科技有限公司 | 2024-03-19 | — | — | CN | claimed |
| WO-1996000207-A1 | CYCLOHEXANONE DERIVATIVES, METHOD OF PREPARING THEM AND INTERMEDIATES USED IN THE METHOD | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-01-04 | — | — | WO | claimed |
| EP-0689544-A1 | PROCESS FOR PRODUCTION OF AN IMIDAZOLE DERIVATIVE | PHARMACIA & UPJOHN COMPANY (US) | 1996-01-03 | — | — | EP | claimed |
| US-5457194-A | Immunosuppressants | ABBOTT LABORATORIES (US) | 1995-10-10 | — | — | US | claimed |
| WO-1995023225-A2 | METHOD AND REAGENT FOR INHIBITING THE EXPRESSION OF DISEASE RELATED GENES | RIBOZYME PHARMACEUTICALS, INC. (US) | 1995-08-31 | — | — | WO | claimed |
| WO-1994021641-A1 | PROCESS FOR PRODUCTION OF AN IMIDAZOLE DERIVATIVE | THE UPJOHN COMPANY (US) | 1994-09-29 | — | — | WO | claimed |
| CN-1085212-A | Indole derivatives | GLAXO SPA (IT) | 1994-04-13 | — | — | CN | claimed |
| EP-0568136-A1 | Indole-2-carboxylic acid derivatives | GLAXO S.p.A. (IT) | 1993-11-03 | — | — | EP | claimed |
| EP-0229922-B1 | NOVEL 2,2'-BI-1H-IMIDAZOLES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-04-15 | — | — | EP | claimed |
| EP-0229922-A2 | Novel 2,2'-BI-1H-imidazoles | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-07-29 | — | — | EP | claimed |
| EP-0070588-B1 | METHOD OF PREPARING 1-ALPHA-HYDROXYVITAMIN D AND 1-ALPHA-HYDROXY-PREVITAMIN D COMPOUNDS, AND ADDUCT OF A PREVITAMIN D OR TACHYSTEROL COMPOUND WITH A SUITABLE DIENOPHILE | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1986-05-07 | — | — | EP | claimed |