Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.66 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29469368 | 1.00 | CYP2A6 (0.66) | CYP2A6DYRK1APTPRCPTPN6PTPN11 | |
| SCHEMBL6399446 | 0.89 | CYP2A6 (0.54) | CYP2A6DYRK1APTPRCPTPN6PTPN11 | |
| SCHEMBL6399444 | 0.84 | CYP2A6 (0.49) | CYP2A6DYRK1APTPRCPTPN6PTPN11 | |
| SCHEMBL7465357 | 0.83 | CYP2A6 (0.46) | CYP2A6DYRK1APTPRCPTPN6PTPN11 | |
| SCHEMBL112311 | 0.79 | CYP2A6 (1.00) | CYP2A6DYRK1APTPRCPTPN6PTPN11 | |
| SCHEMBL202117 | 0.79 | CYP2A6 (0.66) | CYP2A6DYRK1APTPRCPTPN6PTPN11 | |
| SCHEMBL202744 | 0.79 | CYP2A6 (0.66) | CYP2A6DYRK1APTPRCPTPN6PTPN11 | |
| SCHEMBL6607954 | 0.79 | CYP2A6 (0.66) | CYP2A6DYRK1APTPRCPTPN6PTPN11 | |
| SCHEMBL1774025 | 0.79 | CYP2A6 (0.66) | CYP2A6DYRK1APTPRCPTPN6PTPN11 | |
| SCHEMBL8051994 | 0.79 | CYP2A6 (0.66) | CYP2A6DYRK1APTPRCPTPN6PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11236062-B2 | Method for producing 5-(bromomethyl)-1-benzothiophene | FUJIFILM TOYAMA CHEMICAL CO., LTD. (JP) | 2022-02-01 | — | — | US | claimed |
| CN-109526218-B | Preparation method of 5-bromomethyl-1-benzothiophene | 富士胶片富山化学株式会社 | 2021-07-06 | — | — | CN | claimed |
| EP-3444243-B1 | METHOD FOR PRODUCING 5-(BROMOMETHYL)-1-BENZOTHIOPHENE | FUJIFILM TOYAMA CHEMICAL CO LTD (JP) | 2020-09-02 | — | — | EP | claimed |
| US-20190119242-A1 | METHOD FOR PRODUCING 5-(BROMOMETHYL)-1-BENZOTHIOPHENE | FUJIFILM TOYAMA CHEMICAL CO., LTD. (JP) | 2019-04-25 | — | — | US | claimed |
| CN-109526218-A | The preparation method of 5- bromomethyl -1- benzothiophene | 富士胶片富山化学株式会社 | 2019-03-26 | — | — | CN | claimed |
| EP-3444243-A1 | METHOD FOR PRODUCING 5-(BROMOMETHYL)-1-BENZOTHIOPHENE | FUJIFILM Toyama Chemical Co., Ltd. (JP) | 2019-02-20 | — | — | EP | claimed |
| US-20240391940-A1 | FUSED RING-CONTAINING COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | GENEROS BIOPHARMA LTD. (GB) | 2024-11-28 | — | — | US | disclosed |
| CN-118047780-A | Quinazoline heterocyclic compound and anti-infection and anti-tumor application thereof | 中国医学科学院药物研究所 | 2024-05-17 | — | — | CN | disclosed |
| EP-4234544-A1 | FUSED RING-CONTAINING COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | Generos Biopharma Ltd. (KY) | 2023-08-30 | — | — | EP | disclosed |
| EP-4234544-A1 | FUSED RING-CONTAINING COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | Generos Biopharma Ltd. (KY) | 2023-08-30 | — | — | EP | disclosed |
| CN-116457347-A | Compound containing condensed rings, application thereof and composition containing compound | 健艾仕生物医药有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-114478482-A | Compound containing condensed ring, application thereof and composition containing compound | 健艾仕生物医药有限公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2022083731-A1 | FUSED RING-CONTAINING COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | 健艾仕生物医药有限公司 | 2022-04-28 | — | — | WO | disclosed |
| US-5776983-A | ANTIDIABETIC AGENTS, OBESITY, GASTROINTESTINAL DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-07-07 | — | — | US | disclosed |
| WO-1997009311-A1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-13 | — | — | WO | disclosed |
| EP-0659737-A2 | Catecholamine surrogates useful as B3 agonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-06-28 | — | — | EP | disclosed |
| US-5194435-A | Hypoglycemic Agent | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-03-16 | — | — | US | disclosed |
| US-5183825-A | Antidiabetic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-02-02 | — | — | US | disclosed |
| US-4611059-A | THROMBOXANE A2(TXA2) SYNTHETASE INHIBITORS | THE UPJOHN COMPANY (US) | 1986-09-09 | — | — | US | disclosed |
| EP-0069521-A2 | Pyridinyl and imidazolyl derivatives of benzofurans and benzothiophenes | THE UPJOHN COMPANY (US) | 1983-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11236062-B2 | Method for producing 5-(bromomethyl)-1-benzothiophene | BBOX1, BRD1, BRD7 | CYP2A6 420/4885DYRK1A 2796/4885PTPRC 4027/4885 |
| US-20240391940-A1 | FUSED RING-CONTAINING COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | STAT5A, STAT5B, JAK2 | CYP2A6 3288/4885DYRK1A 1243/4885PTPRC 161/4885 |
| US-20190119242-A1 | METHOD FOR PRODUCING 5-(BROMOMETHYL)-1-BENZOTHIOPHENE | BBOX1, BRD1, BRD7 | CYP2A6 420/4885DYRK1A 2796/4885PTPRC 4027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.