Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.35 |
| ▸ | WNT3A | P56704 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29469368 | 0.89 | CYP2A6 (0.66) | CYP2A6SLC6A4SLC6A3SLC6A2PDE10A | |
| SCHEMBL1863293 | 0.89 | CYP2A6 (0.66) | CYP2A6SLC6A4SLC6A3SLC6A2PDE10A | |
| SCHEMBL155613 | 0.84 | CYP2A6 (0.50) | CYP2A6SLC6A4SLC6A3SLC6A2CA12 | |
| SCHEMBL29698806 | 0.84 | CYP2A6 (0.50) | CYP2A6SLC6A4SLC6A3SLC6A2CA12 | |
| SCHEMBL20198725 | 0.82 | CYP2A6 (0.53) | CYP2A6SLC6A4SLC6A3SLC6A2PDE10A | |
| SCHEMBL28744582 | 0.78 | CYP2A6 (0.50) | CYP2A6SLC6A4SLC6A3SLC6A2CA12 | |
| SCHEMBL7465357 | 0.78 | CYP2A6 (0.46) | CYP2A6SLC6A4SLC6A3SLC6A2DYRK1A | |
| SCHEMBL3565973 | 0.78 | CYP1A2 (0.59) | CYP2A6SLC6A4SLC6A3SLC6A2CA12 | |
| SCHEMBL4312702 | 0.76 | CYP2A6 (0.61) | CYP2A6SLC6A4SLC6A3SLC6A2CA12 | |
| Oxirane SCHEMBL826986 | 0.75 | SLC6A2 (0.45) | CYP2A6SLC6A4SLC6A3SLC6A2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288376-A1 | Bicyclyl or heterobicyclylmethanesulfonylanimo-substituted N-hydroxyformamides | SMITHKLINE BEECHAM PLC | 2005-12-29 | — | — | US | disclosed |
| US-20040024066-A1 | Bicyclyl or heterobicyclylmethanesulfonylamino-substituted n-hydroxyformamides | SMITHKLINE BEECHAM P.L.C. (GB) | 2004-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288376-A1 | Bicyclyl or heterobicyclylmethanesulfonylanimo-substituted N-hydroxyformamides | CD22, CD2, NEU3 | CYP2A6 486/4885SLC6A4 1743/4885SLC6A3 285/4885 |
| US-20040024066-A1 | Bicyclyl or heterobicyclylmethanesulfonylamino-substituted n-hydroxyformamides | CD22, CD2, NEU3 | CYP2A6 459/4885SLC6A4 1507/4885SLC6A3 303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.