Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 4/20 | 0.45 |
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18634022 | 0.84 | MC4R (0.57) | NPC1RAB9ATP53ALDH1A1LMNA | |
| SCHEMBL4551705 | 0.80 | POLB (0.47) | LMNA | |
| SCHEMBL18634104 | 0.78 | POLB (0.36) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL18634107 | 0.75 | CYP19A1 (0.40) | TP53TSHR | |
| SCHEMBL15467001 | 0.74 | HRH3 (0.87) | HRH3SMN1; SMN2CYP2A13HIF1AEPAS1 | |
| SCHEMBL18634027 | 0.74 | ALDH1A1 (0.42) | HRH3SMN1; SMN2TSHRLTA4HALDH1A1 | |
| SCHEMBL18634150 | 0.74 | NOD1 (0.35) | MEN1KMT2A | |
| SCHEMBL6200777 | 0.73 | SIGMAR1 (0.71) | HRH3SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL102338 | 0.73 | SIGMAR1 (0.71) | HRH3SMN1; SMN2NPC1RAB9ATSHR | |
| Water SCHEMBL1702298 | 0.71 | SIGMAR1 (0.68) | HRH3SMN1; SMN2NPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885718-B1 | FLUORESCENT CHEMICAL COMPOUNDS HAVING HIGH SELECTIVITY FOR DOUBLE STRANDED DNA, AND METHODS FOR THEIR USE | LIFE TECHNOLOGIES CORP (US) | 2017-03-15 | — | — | EP | disclosed |