SCHEMBL18635573

SCHEMBL18635573

[N-]=[N+]=NCCCCCC(N)=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDUA P35475 2/20 0.38
SOAT1 P35610 2/20 0.36
TP53 P04637 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2C19 P33261 2/20 0.36
MEN1 O00255 1/20 0.36
FAAH O00519 1/20 0.36
KMT2A Q03164 1/20 0.36
CHRM2 P08172 2/20 0.35
CHRM4 P08173 2/20 0.35
CHRM1 P11229 2/20 0.35
KDM4E B2RXH2 3/20 0.33
CNR2 P34972 1/20 0.32
GMNN O75496 1/20 0.32
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
GLA P06280 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19194629 1.00 IDUA (0.38) IDUASOAT1TP53CYP1A2CYP3A4
SCHEMBL13772507 1.00 IDUA (0.38) IDUASOAT1TP53CYP1A2CYP3A4
SCHEMBL25257297 1.00 IDUA (0.38) IDUASOAT1TP53CYP1A2CYP3A4
SCHEMBL30684791 1.00 IDUA (0.38) IDUASOAT1TP53CYP1A2CYP3A4
SCHEMBL16006898 0.98 IDUA (0.36) IDUASOAT1TP53CYP1A2CYP3A4
SCHEMBL13464378 0.91
SCHEMBL16059643 0.83
SCHEMBL13736453 0.82 TSHR (0.55) MEN1KMT2AALDH1A1LMNAALOX15
SCHEMBL25408049 0.82 TSHR (0.55) MEN1KMT2AALDH1A1LMNAALOX15
SCHEMBL20626797 0.82 TSHR (0.55) MEN1KMT2AALDH1A1LMNAALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250262317-A1 LINKERS FOR SITE-SPECIFIC ANTIBODY CONJUGATION HOFFMANN-LA ROCHE INC. (US) 2025-08-21 US claimed
EP-4558174-A1 LINKERS FOR SITE-SPECIFIC ANTIBODY CONJUGATION F. Hoffmann-La Roche AG (CH) 2025-05-28 EP claimed
WO-2024017923-A1 LINKERS FOR SITE-SPECIFIC ANTIBODY CONJUGATION F. HOFFMANN-LA ROCHE AG (CH) 2024-01-25 WO claimed
US-20250262317-A1 LINKERS FOR SITE-SPECIFIC ANTIBODY CONJUGATION HOFFMANN-LA ROCHE INC. (US) 2025-08-21 US disclosed
WO-2025120218-A1 CD16A-BINDING POLYPEPTIDE ONCOPEPTIDES INNOVATION 1 AB (SE) 2025-06-12 WO disclosed
EP-4558174-A1 LINKERS FOR SITE-SPECIFIC ANTIBODY CONJUGATION F. Hoffmann-La Roche AG (CH) 2025-05-28 EP disclosed
WO-2024087332-A1 BIFUNCTIONAL COMPOUND USED AS TARGET PROTEIN DEGRADATION AGENT AND USE THEREOF IN TARGET PROTEIN LYSOSOMAL DEGRADATION 深圳先进技术研究院 2024-05-02 WO disclosed
WO-2024017923-A1 LINKERS FOR SITE-SPECIFIC ANTIBODY CONJUGATION F. HOFFMANN-LA ROCHE AG (CH) 2024-01-25 WO disclosed
CN-117263999-A Camptothecin prodrugs and pharmaceutical compositions thereof 天津和美奥康医药科技有限公司 2023-12-22 CN disclosed
CN-116457023-A antibody-TLR agonist conjugates, methods and uses thereof AMBRX公司 2023-07-18 CN disclosed
US-20210228530-A1 TAXANE-LIPID-POLYSACCHARIDE DUAL CONJUGATES, PREPARATION METHODS THEREOF AND USES THEREOF SANTOLECAN PHARMACEUTICALS LLC 2021-07-29 US disclosed
US-20210139549-A1 COMPOUND HAVING AFFINITY SUBSTANCE TO ANTIBODY, CLEAVABLE PORTION, AND REACTIVE GROUP, OR SALT THEREOF AJINOMOTO CO., INC. (JP) 2021-05-13 US disclosed
WO-2020160230-A1 CHEMICAL REPORTER PROBES, KITS, AND METHODS OF USING THE SAME ARTRIS THERAPEUTICS INC. (US) 2020-08-06 WO disclosed
EP-3617235-A1 COMPOUND HAVING SUBSTANCE THAT HAS AFFINITY FOR SOLUBLE PROTEIN, CLEAVABLE MOIETY, AND REACTIVE GROUP, OR SALT THEREOF Ajinomoto Co., Inc. (JP) 2020-03-04 EP disclosed
US-20170072037-A1 Xenoantigen-Displaying Anti-Cancer Vaccines and Method of Making THE UNIVERSITY OF TOLEDO (US) 2017-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250262317-A1 LINKERS FOR SITE-SPECIFIC ANTIBODY CONJUGATION DAO, RNGTT, CTDSP1 IDUA 234/4885SOAT1 2056/4885TP53 4383/4885
US-20210228530-A1 TAXANE-LIPID-POLYSACCHARIDE DUAL CONJUGATES, PREPARATION METHODS THEREOF AND USES THEREOF DDOST, UGT2B17, UGT1A7 IDUA 1912/4885SOAT1 302/4885TP53 2361/4885
US-20170072037-A1 Xenoantigen-Displaying Anti-Cancer Vaccines and Method of Making CSGALNACT1, B3GAT3, LGALS3BP IDUA 71/4885SOAT1 959/4885TP53 115/4885
US-20210139549-A1 COMPOUND HAVING AFFINITY SUBSTANCE TO ANTIBODY, CLEAVABLE PORTION, AND REACTIVE GROUP, OR SALT THEREOF FCGR3B, FCGR2A, FCGR1A IDUA 96/4885SOAT1 3254/4885TP53 3644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.