Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13637310 | 0.88 | MCHR1 (0.35) | LMNAMMP2MMP8MMP13SCD | |
| SCHEMBL13662226 | 0.86 | KCNH2 (0.43) | LMNAMMP2MMP8MMP13SCD | |
| SCHEMBL18116829 | 0.84 | KCNH2 (0.44) | LMNASCDKCNH2MAPTALDH1A1 | |
| SCHEMBL13662234 | 0.80 | KCNH2 (0.43) | LMNAMMP2MMP8MMP13SCD | |
| SCHEMBL13637216 | 0.78 | KCNH2 (0.35) | MMP2MMP8MMP13KCNH2SMN1; SMN2 | |
| SCHEMBL13663814 | 0.77 | NT5E (0.41) | KCNH2MAPTHPGD | |
| SCHEMBL18638158 | 0.75 | KCNH2 (0.41) | LMNAMMP2MMP8MMP13SCD | |
| SCHEMBL13637125 | 0.74 | MCHR1 (0.34) | KCNH2POLB | |
| SCHEMBL13662230 | 0.73 | KCNH2 (0.41) | LMNANPC1RAB9AKCNH2MAPT | |
| SCHEMBL13662231 | 0.72 | KCNH2 (0.40) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3141905-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | Promega Corporation (US) | 2017-03-15 | — | — | EP | disclosed |