Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13637242 | 0.87 | ITPR3 (0.33) | KCNH2SMN1; SMN2TP53 | |
| SCHEMBL13662226 | 0.85 | KCNH2 (0.43) | KCNH2MMP2MMP8MMP13MAPT | |
| SCHEMBL18116829 | 0.83 | KCNH2 (0.44) | KCNH2MAPTPOLB | |
| SCHEMBL13662234 | 0.79 | KCNH2 (0.43) | KCNH2MMP2MMP8MMP13MAPT | |
| SCHEMBL18638161 | 0.78 | LMNA (0.36) | KCNH2MMP2MMP8MMP13MAPT | |
| SCHEMBL13663814 | 0.77 | NT5E (0.41) | KCNH2MAPT | |
| SCHEMBL13637310 | 0.75 | MCHR1 (0.35) | KCNH2MMP2MMP8MMP13MAPT | |
| SCHEMBL18638158 | 0.74 | KCNH2 (0.41) | KCNH2MMP2MMP8MMP13MAPT | |
| SCHEMBL13662230 | 0.73 | KCNH2 (0.41) | KCNH2MAPT | |
| SCHEMBL13662231 | 0.72 | KCNH2 (0.40) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009142678-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | PROMEGA CORPORATIN (US) | 2009-11-26 | — | — | WO | disclosed |