Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21549531 | 0.92 | TP53 (0.46) | KCNH2HDAC6HDAC1HDAC10HDAC2 | |
| SCHEMBL21549540 | 0.92 | TP53 (0.46) | KCNH2HDAC6HDAC1HDAC10HDAC2 | |
| SCHEMBL21549533 | 0.91 | KCNH2 (0.43) | KCNH2HDAC6HDAC1HDAC10HDAC2 | |
| SCHEMBL20353098 | 0.90 | KCNH2 (0.44) | KCNH2HDAC6HDAC1HDAC10HDAC2 | |
| SCHEMBL21549529 | 0.89 | FTO (0.50) | KCNH2HDAC6HPGDNT5EKMT2A | |
| SCHEMBL29923531 | 0.84 | KCNH2 (0.41) | KCNH2HPGDALDH1A1NT5EKMT2A | |
| SCHEMBL27087685 | 0.84 | KCNH2 (0.41) | KCNH2HPGDALDH1A1NT5EKMT2A | |
| SCHEMBL23509569 | 0.83 | KCNH2 (0.48) | KCNH2HDAC6HDAC1HDAC10HDAC2 | |
| SCHEMBL16745258 | 0.82 | P2RY6 (0.42) | KCNH2HPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL22600489 | 0.82 | KCNH2 (0.47) | KCNH2HDAC6HDAC1HDAC10HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655247-B2 | Nanoluc suicide substrates | PROMEGA CORPORATION (US) | 2023-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655247-B2 | Nanoluc suicide substrates | XIAP, NLN, BAD | KCNH2 3345/4885HDAC6 2903/4885HDAC1 803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.