Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18639981 | 0.88 | MAOA (0.50) | CHEK1MAOBMAOAPARP15PARP10 | |
| SCHEMBL18639866 | 0.86 | PARP15 (0.51) | MAOBMAOAPARP15PARP10 | |
| SCHEMBL18639974 | 0.85 | CHEK1 (0.45) | CHEK1MAOBMAOAPARP15PARP10 | |
| SCHEMBL18640109 | 0.84 | PARP10 (0.53) | MAOBMAOAPARP15PARP10 | |
| SCHEMBL18640024 | 0.83 | CYP4F2 (0.53) | LRRK2 | |
| SCHEMBL18640136 | 0.83 | PARP10 (0.54) | MAOBMAOAPARP15PARP10 | |
| SCHEMBL18639947 | 0.82 | F10 (0.54) | MAOBMAOAACHE | |
| SCHEMBL18639846 | 0.82 | CYP4F2 (0.41) | PARP15PARP10 | |
| SCHEMBL18639875 | 0.82 | DRD2 (0.43) | — | |
| SCHEMBL18639956 | 0.82 | SLC6A2 (0.53) | MAOBMAOAPARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017045751-A1 | COMPOUNDS AS ASIC INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-03-23 | — | — | WO | disclosed |
| WO-2017045751-A1 | COMPOUNDS AS ASIC INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-03-23 | — | — | WO | disclosed |