Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7059292 | 0.81 | SMN1; SMN2 (0.60) | RAB9ANPC1SMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL3820618 | 0.77 | HTT (0.66) | RAB9ANPC1SMN1; SMN2ALDH1A1DHODH | |
| SCHEMBL8797089 | 0.77 | NAMPT (0.55) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9538774 | 0.77 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL8604699 | 0.76 | DHODH (0.64) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL18640728 | 0.76 | DHODH (0.64) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL15528812 | 0.76 | MAPK1 (0.71) | RAB9ANPC1SMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL6612630 | 0.75 | HTT (0.56) | RAB9ANPC1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL23796859 | 0.74 | DHODH (0.53) | RAB9ANPC1SMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL8800517 | 0.74 | KMT2A (0.67) | RAB9ANPC1SMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362436-B1 | PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS | UNIV ANTWERPEN (BE) | 2021-06-30 | — | — | EP | disclosed |
| EP-3362436-A1 | PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS | Universiteit Antwerpen (BE) | 2018-08-22 | — | — | EP | disclosed |
| WO-2017046133-A1 | PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS | UNIVERSITEIT ANTWERPEN (BE) | 2017-03-23 | — | — | WO | disclosed |