Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18640732 | 0.86 | HTT (0.76) | HTTRAB9AALDH1A1HPGDNPC1 | |
| SCHEMBL23566382 | 0.85 | KDM4E (0.51) | HTTRAB9AALDH1A1HPGDNPC1 | |
| SCHEMBL18640787 | 0.82 | HTT (0.69) | HTTRAB9AALDH1A1HPGDNPC1 | |
| SCHEMBL18640752 | 0.82 | HTT (1.00) | HTTRAB9AALDH1A1HPGDNPC1 | |
| SCHEMBL5005730 | 0.80 | HTT (0.43) | HTTRAB9AALDH1A1HPGDNPC1 | |
| SCHEMBL3820618 | 0.80 | HTT (0.66) | HTTRAB9AALDH1A1HPGDNPC1 | |
| SCHEMBL8126889 | 0.79 | ALDH1A1 (0.44) | HTTRAB9AALDH1A1HPGDNPC1 | |
| SCHEMBL9842635 | 0.79 | RAB9A (0.68) | HTTRAB9AALDH1A1HPGDNPC1 | |
| SCHEMBL23566421 | 0.78 | HTT (0.43) | HTTRAB9AALDH1A1HPGDNPC1 | |
| SCHEMBL18640733 | 0.77 | HTT (0.63) | HTTRAB9AALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362436-B1 | PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS | UNIV ANTWERPEN (BE) | 2021-06-30 | — | — | EP | disclosed |