Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.59 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.59 |
| ▸ | BAX | Q07812 | 1/20 | 0.59 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,4-Dimethoxybenzene SCHEMBL7460138 | 0.88 | BACE1 (0.59) | LTA4HNR1H2BAXGSTP1ALOX5 | |
| SCHEMBL14283896 | 0.87 | GSTP1 (0.64) | LTA4HNR1H2BAXGSTP1BACE1 | |
| SCHEMBL9504663 | 0.83 | ALOX5 (0.65) | ALOX5BACE1ESR2PELI1ESR1 | |
| SCHEMBL29458798 | 0.82 | ALOX5 (0.71) | ALOX5BACE1ESR2PELI1ESR1 | |
| SCHEMBL68984 | 0.82 | ALOX5 (0.71) | ALOX5BACE1ESR2PELI1ESR1 | |
| SCHEMBL589665 | 0.81 | BACE1 (0.60) | LTA4HNR1H2BAXGSTP1ALOX5 | |
| SCHEMBL13861252 | 0.80 | PELI1 (0.53) | ALOX5BACE1ESR2PELI1ESR1 | |
| Ethyne SCHEMBL29161596 | 0.79 | ALOX5 (0.61) | ALOX5BACE1ESR2PELI1ESR1 | |
| SCHEMBL9149016 | 0.79 | ALOX5 (0.59) | LTA4HNR1H2BAXGSTP1ALOX5 | |
| Phenol SCHEMBL28262809 | 0.79 | ALOX5 (0.65) | ALOX5BACE1ESR2PELI1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046862-B1 | POLY(ARYL ETHER) WITH PENDENT SULFONIC ACID PHENYL GROUPS | CA NAT RESEARCH COUNCIL (CA) | 2013-02-13 | — | — | EP | disclosed |
| US-7947800-B2 | Poly(aryl ether) with pendent sulfonic acid phenyl groups | NATIONAL RESEARCH COUNCIL OF CANADA | 2011-05-24 | — | — | US | disclosed |
| CN-101225035-B | Biphenol monomer containing anthracene benzophenone substituent as well as preparation method and use thereof | UNIV JILIN | 2010-06-09 | — | — | CN | disclosed |
| US-20090203806-A1 | POLY(ARYL ETHER) WITH PENDENT SULFONIC ACID PHENYL GROUPS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2009-08-13 | — | — | US | disclosed |
| EP-2046862-A1 | POLY(ARYL ETHER) WITH PENDENT SULFONIC ACID PHENYL GROUPS | National Research Council of Canada (CA) | 2009-04-15 | — | — | EP | disclosed |
| CN-101225035-A | Biphenol monomer containing anthracene benzophenone substituent as well as preparation method and use thereof | UNIV JILIN (CN) | 2008-07-23 | — | — | CN | disclosed |
| WO-2008009102-A1 | POLY(ARYL ETHER) WITH PENDENT SULFONIC ACID PHENYL GROUPS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2008-01-24 | — | — | WO | disclosed |