SCHEMBL589665

SCHEMBL589665

Oc1ccc(Oc2ccc(O)c(-c3ccccc3)c2)cc1-c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 3/20 0.60
THRA P10827 6/20 0.56
THRB P10828 6/20 0.56
ALDH1A1 P00352 1/20 0.52
HPGD P15428 1/20 0.52
BCL2L1 Q07817 1/20 0.52
HSD17B10 Q99714 1/20 0.52
PELI1 Q96FA3 1/20 0.51
GSTP1 P09211 1/20 0.47
ALOX5 P09917 2/20 0.47
HSD17B1 P14061 1/20 0.46
HSD17B2 P37059 1/20 0.46
LTA4H P09960 1/20 0.45
NR1H2 P55055 1/20 0.45
BAX Q07812 1/20 0.45
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HDAC8 Q9BY41 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12323966 0.89 NCOA1 (0.56) BACE1THRATHRBALDH1A1HPGD
SCHEMBL8634786 0.85 PNLIP (0.47) BACE1THRATHRBALDH1A1PELI1
SCHEMBL9638313 0.84 MAPT (0.60) BACE1THRATHRBHPGDPELI1
SCHEMBL1864162 0.81 LTA4H (0.59) BACE1THRATHRBPELI1GSTP1
SCHEMBL14283896 0.81 GSTP1 (0.64) BACE1GSTP1LTA4HNR1H2BAX
SCHEMBL13445888 0.80 GSTP1 (0.52) BACE1ALDH1A1GSTP1ALOX5LTA4H
SCHEMBL16429141 0.80 GAA (0.56) BACE1THRATHRBALDH1A1HPGD
SCHEMBL9713452 0.79 BACE1 (0.46) BACE1THRATHRBALDH1A1HPGD
SCHEMBL12323955 0.79 NCOA1 (0.49) BACE1THRATHRBALDH1A1HPGD
SCHEMBL9510350 0.78 BACE1 (0.66) BACE1THRATHRBALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1339797-B1 TRANSPARENT POLYCARBONATE POLYESTER COMPOSITION AND PROCESS SABIC INNOVATIVE PLASTICS IP (NL) 2013-04-10 EP disclosed
US-8114928-B2 Transparent polycarbonate polyester composition and process SABIC INNOVATIVE PLASTICS IP BV (NL) 2012-02-14 US disclosed
EP-1576053-B1 STATIC DISSIPATING RESIN COMPOSITION AND METHODS FOR MANUFACTURE THEREOF SABIC INNOVATIVE PLASTICS IP (NL) 2011-06-29 EP disclosed
US-20110086951-A1 Transparent Polycarbonate Polyester Composition and Process SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-04-14 US disclosed
US-7767738-B2 Transparent polycarbonate polyester composition and process SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-08-03 US disclosed
US-7700714-B2 Optical element and achromatic lens TEIJIN CHEMICALS, LTD. (JP) 2010-04-20 US disclosed
US-20090143560-A1 Optical Element and Achromatic Lens TEIJIN CHEMICALS, LTD. 2009-06-04 US disclosed
EP-1947131-A1 OPTICAL DEVICE AND ACHROMATIC LENS Teijin Chemicals, Ltd. (JP) 2008-07-23 EP disclosed
EP-1358268-B1 FLAME RETARDANT POLYCARBONATE POLYESTER COMPOSITION GEN ELECTRIC (US) 2008-06-11 EP disclosed
US-20070049703-A1 STATIC DISSIPATING RESIN COMPOSITIONS, METHODS FOR MANUFACTURE AND ARTICLES MADE THEREFROM CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-01 US disclosed
WO-2000052096-A1 COMPOSITION AND ARTICLE FOR OPTICAL DATA STORAGE DEVICES GENERAL ELECTRIC COMPANY (US) 2000-09-08 WO disclosed
US-5585212-A LAYER HAVING BLEND OF HIGHER AND LOWER MOLECULAR WEIGHT POLYCARBONATES WITH CHARGE GENERATING AND CHARGE TRANSPORTING MATERIALS, SENSITIVITY, DURABILITY, STRENGTH, EASE OF MANUFACTURE MINOLTA CO., LTD. (JP) 1996-12-17 US disclosed
EP-0411192-B1 Electrophotographic photoreceptor IDEMITSU KOSAN CO (JP) 1995-06-07 EP disclosed
US-5151531-A DIHYDRIC PHENOLS IDEMITSU KOSAN CO., LTD. (JP) 1992-09-29 US disclosed
EP-0249963-B1 POLYCARBONATES IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-04-22 EP disclosed
EP-0411192-A1 Electrophotographic photoreceptor IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-02-06 EP disclosed
US-4985326-A PHOTOSENSITIVE LAYER CONTAINING A POLYCARBONATE AS BINDER RESIN IDEMITSU KOSAN CO., LTD. (JP) 1991-01-15 US disclosed
US-4892924-A Polycarbonate containing compound from bis(3-phenyl-4-hydroxyphenyl) IDEMITSU KOSAN CO., LTD. (JP) 1990-01-09 US disclosed
EP-0329991-A1 Aromatic polycarbonate film IDEMITSU KOSAN COMPANY LIMITED (JP) 1989-08-30 EP disclosed
EP-0249963-A2 Polycarbonates IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-12-23 EP disclosed