SCHEMBL9149016

SCHEMBL9149016

Oc1ccc(-c2ccc(Oc3ccc(-c4ccc(O)cc4O)cc3)cc2)c(O)c1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.59
ESR2 Q92731 4/20 0.54
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
ESR1 P03372 3/20 0.54
GAA P10253 3/20 0.47
LTA4H P09960 2/20 0.46
NR1H2 P55055 1/20 0.46
BAX Q07812 1/20 0.46
GSTP1 P09211 1/20 0.44
HSD17B10 Q99714 2/20 0.43
LMNA P02545 2/20 0.43
MAPT P10636 2/20 0.43
ALOX12 P18054 2/20 0.43
TP53 P04637 1/20 0.43
TSHR P16473 1/20 0.43
HTT P42858 1/20 0.43
HSP90AA1 P07900 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278379 0.84 ALOX5 (0.73) ALOX5ESR2ESR1HSD17B10
SCHEMBL1847771 0.83 GAA (0.65) ALOX5ESR2MEN1KMT2AESR1
SCHEMBL3811869 0.81 ALOX5 (0.70) ALOX5ESR2MEN1KMT2AESR1
SCHEMBL1864162 0.79 LTA4H (0.59) ALOX5ESR2MEN1KMT2AESR1
SCHEMBL7622171 0.77 ESR2 (0.65) ESR2MEN1KMT2AESR1GAA
SCHEMBL1719891 0.76 LTA4H (0.50) ALOX5ESR2MEN1KMT2AESR1
SCHEMBL1720471 0.76 LTA4H (0.50) ALOX5ESR2MEN1KMT2AESR1
SCHEMBL28298032 0.76 GSTP1 (0.51) ALOX5MEN1KMT2AGAALTA4H
SCHEMBL8663280 0.76 ESR2 (0.82) ESR2MEN1KMT2AESR1LTA4H
SCHEMBL9581090 0.76 ESR2 (0.82) ESR2MEN1KMT2AESR1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0468477-B1 Process for producing dihydric phenols DAINIPPON INK & CHEMICALS (JP) 1995-01-11 EP disclosed
US-5138104-A Reacting a phenol with a ketone peroxide in the presence of compound with at least one phosphorus-sulfur bond DAINIPPON INK AND CHEMICALS, INC. (JP) 1992-08-11 US disclosed
EP-0468477-A1 Process for producing dihydric phenols DAINIPPON INK AND CHEMICALS, INC. (JP) 1992-01-29 EP disclosed