SCHEMBL18643288

SCHEMBL18643288

C=CC(=O)N(CCC(C)C)CC(O)CO

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12254042 0.85 ZDHHC20 (0.40) ZDHHC20ZDHHC2ALDH1A1TSHR
SCHEMBL22420161 0.82 ZDHHC20 (0.39) ZDHHC20ZDHHC2ALDH1A1TSHR
SCHEMBL410928 0.82 ZDHHC20 (0.48) ZDHHC20ZDHHC2ALDH1A1TSHR
SCHEMBL12643371 0.79 ZDHHC20 (0.35) ZDHHC20ZDHHC2
SCHEMBL18469449 0.79 ZDHHC20 (0.35) ZDHHC20ZDHHC2
SCHEMBL19801200 0.77 ALDH1A1 (0.38) ZDHHC20ZDHHC2ALDH1A1TSHR
SCHEMBL17485730 0.77 ZDHHC20 (0.35) ZDHHC20ZDHHC2
SCHEMBL14528303 0.76 ZDHHC20 (0.34) ZDHHC20ZDHHC2TSHR
SCHEMBL3208029 0.75 ZDHHC20 (0.42) ZDHHC20ZDHHC2ALDH1A1TSHR
SCHEMBL26637804 0.74 ZDHHC20 (0.38) ZDHHC20ZDHHC2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2705390-B2 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME JOHNSON & JOHNSON VISION CARE (US) 2023-11-15 EP disclosed
EP-3141933-B9 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME JOHNSON & JOHNSON VISION CARE (US) 2019-11-13 EP disclosed
EP-3141933-B1 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME JOHNSON & JOHNSON VISION CARE (US) 2019-05-22 EP disclosed
EP-3473662-A1 SILICONE HYDROGELS FORMED FROM ZERO DILUENT REACTIVE MIXTURES Johnson & Johnson Vision Care Inc. (US) 2019-04-24 EP disclosed
EP-2794724-B9 SILICONE HYDROGELS FORMED FROM ZERO DILUENT REACTIVE MIXTURES JOHNSON & JOHNSON VISION CARE (US) 2019-01-09 EP disclosed
EP-2794724-B1 SILICONE HYDROGELS FORMED FROM ZERO DILUENT REACTIVE MIXTURES JOHNSON & JOHNSON VISION CARE (US) 2018-07-18 EP disclosed
EP-2855544-B1 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE (US) 2018-06-20 EP disclosed
EP-3296334-A1 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME Johnson & Johnson Vision Care Inc. (US) 2018-03-21 EP disclosed
EP-3141933-A1 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME Johnson & Johnson Vision Care Inc. (US) 2017-03-15 EP disclosed