Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14297002 | 0.87 | POLB (0.42) | POLBMAPTALDH1A1HPGDGAA | |
| SCHEMBL13625396 | 0.86 | POLB (0.47) | POLBMAPTALDH1A1HPGDGAA | |
| SCHEMBL4400681 | 0.85 | POLB (0.46) | POLBMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL13644620 | 0.85 | POLB (0.40) | POLBMAPTALDH1A1HPGDGAA | |
| SCHEMBL13625469 | 0.84 | POLB (0.45) | POLBMAPTALDH1A1HPGDGAA | |
| SCHEMBL13643864 | 0.84 | POLB (0.47) | POLBMAPTALDH1A1HPGDGAA | |
| SCHEMBL16404365 | 0.84 | POLB (0.45) | POLBMAPTALDH1A1HPGDGAA | |
| SCHEMBL14297023 | 0.83 | ALDH1A1 (0.57) | POLBMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL14297017 | 0.82 | POLB (0.48) | POLBMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL23274221 | 0.82 | POLB (0.43) | POLBMAPTALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2793928-B1 | PROCESS FOR PURIFYING A SAMPLE OF H38C2 ANTIBODY | PFIZER (US) | 2017-03-15 | — | — | EP | disclosed |