Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14297017 | 0.89 | POLB (0.48) | POLBALDH1A1HPGDNAMPTMAPT | |
| SCHEMBL14297024 | 0.87 | POLB (0.47) | POLBALDH1A1HPGDNAMPTMAPT | |
| SCHEMBL13643864 | 0.86 | POLB (0.47) | POLBALDH1A1HPGDNAMPTMAPT | |
| SCHEMBL13625396 | 0.86 | POLB (0.47) | POLBALDH1A1HPGDNAMPTMAPT | |
| SCHEMBL4400681 | 0.85 | POLB (0.46) | POLBALDH1A1HPGDNAMPTMAPT | |
| SCHEMBL14297023 | 0.85 | ALDH1A1 (0.57) | POLBALDH1A1HPGDNAMPTMAPT | |
| SCHEMBL16425205 | 0.85 | HPGD (0.50) | POLBALDH1A1HPGDNAMPTNPC1 | |
| SCHEMBL14203798 | 0.84 | HPGD (0.49) | POLBALDH1A1HPGDNAMPTRAB9A | |
| SCHEMBL16404365 | 0.84 | POLB (0.45) | POLBALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL13625469 | 0.84 | POLB (0.45) | POLBALDH1A1HPGDMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230012213-A1 | NOVEL CONJUGATION CHEMISTRY FOR CATALYTIC ANTIBODY 38C2 | THE SCRIPPS RESEARCH INSTITUTE | 2023-01-12 | — | — | US | disclosed |
| EP-4048311-A1 | NOVEL CONJUGATION CHEMISTRY FOR CATALYTIC ANTIBODY 38C2 | University of Florida Research Foundation, Incorporated (US) | 2022-08-31 | — | — | EP | disclosed |
| CN-114846030-A | Novel conjugation chemistry that catalyzes antibody 38C2 | 佛罗里达大学研究基金会公司 | 2022-08-02 | — | — | CN | disclosed |
| WO-2021080846-A1 | NOVEL CONJUGATION CHEMISTRY FOR CATALYTIC ANTTIBODY 38C2 | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230012213-A1 | NOVEL CONJUGATION CHEMISTRY FOR CATALYTIC ANTIBODY 38C2 | PTMS, MRPS34, SDC2 | POLB 1622/4885ALDH1A1 1323/4885HPGD 4842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.