Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.45 |
| ▸ | EGFR | P00533 | 3/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | ABL2 | P42684 | 2/20 | 0.42 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | CTSE | P14091 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CCNK | O75909 | 1/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30111813 | 0.94 | BTK (0.46) | SRCEGFRPIK3CAHCAR1CTSD | |
| SCHEMBL23450731 | 0.94 | BTK (0.46) | SRCEGFRPIK3CAHCAR1CTSD | |
| SCHEMBL18289974 | 0.94 | BTK (0.46) | SRCEGFRPIK3CAHCAR1CTSD | |
| SCHEMBL29737131 | 0.87 | KDM4E (0.37) | SRCEGFRPIK3CAHCAR1GPR119 | |
| SCHEMBL24590579 | 0.87 | KDM4E (0.37) | SRCEGFRPIK3CAHCAR1GPR119 | |
| SCHEMBL15156055 | 0.84 | SRC (0.55) | SRCEGFRPIK3CAABL1ABL2 | |
| SCHEMBL15145742 | 0.84 | SRC (0.55) | SRCEGFRPIK3CAABL1ABL2 | |
| SCHEMBL18644664 | 0.81 | JAK2 (0.49) | SRCEGFRHCAR1GPR119USP30 | |
| SCHEMBL20450694 | 0.80 | CCR5 (0.46) | GPR119BTKCCR5 | |
| SCHEMBL20450695 | 0.80 | CCR5 (0.46) | GPR119BTKCCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017041536-A1 | OXO-DIHYDROIMIDAZO PYRIDINE COMPOUND AND APPLICATIONS THEREOF | 东莞市真兴贝特医药技术有限公司 | 2017-03-16 | — | — | WO | disclosed |