Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | JAK1 | P23458 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18645213 | 0.95 | HTR6 (0.47) | JAK2JAK1HTR6CCR5USP30 | |
| SCHEMBL15171143 | 0.88 | JAK2 (0.49) | JAK2JAK1HTR6CCR5USP30 | |
| SCHEMBL15711178 | 0.88 | JAK2 (0.49) | JAK2JAK1HTR6CCR5USP30 | |
| SCHEMBL28076558 | 0.88 | CALCRL (0.40) | PARP1PARP2ACHE | |
| SCHEMBL28076562 | 0.88 | CALCRL (0.40) | PARP1PARP2ACHE | |
| SCHEMBL30111801 | 0.87 | HTR6 (0.40) | JAK2JAK1HTR6SRCHPGDS | |
| SCHEMBL18289976 | 0.87 | HTR6 (0.40) | JAK2JAK1HTR6SRCHPGDS | |
| SCHEMBL15171260 | 0.84 | HTR6 (0.46) | JAK2JAK1HTR6USP30GPR119 | |
| SCHEMBL16341186 | 0.84 | HTR6 (0.46) | JAK2JAK1HTR6USP30GPR119 | |
| SCHEMBL18645205 | 0.83 | HTR6 (0.55) | JAK2JAK1HTR6USP30PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017041536-A1 | OXO-DIHYDROIMIDAZO PYRIDINE COMPOUND AND APPLICATIONS THEREOF | 东莞市真兴贝特医药技术有限公司 | 2017-03-16 | — | — | WO | disclosed |