Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.39 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ASPH | Q12797 | 1/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12500803 | 0.80 | SIRT6 (0.46) | LMNATSHRTDP1SIRT6GABRA1 | |
| SCHEMBL29185911 | 0.74 | KDM4E (0.41) | HCAR2KDM4ENAPRTALDH1A1ALOX15 | |
| SCHEMBL27252381 | 0.74 | MEN1 (0.49) | HCAR2KDM4ENAPRTALDH1A1ALOX15 | |
| SCHEMBL30241953 | 0.74 | MEN1 (0.49) | HCAR2KDM4ENAPRTALDH1A1ALOX15 | |
| SCHEMBL12500609 | 0.74 | CYP1A2 (0.50) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL20929035 | 0.73 | KDM4E (0.40) | HCAR2KDM4ENAPRTALDH1A1ALOX15 | |
| SCHEMBL28291790 | 0.73 | SIRT6 (0.42) | HCAR2KDM4ENAPRTALDH1A1ALOX15 | |
| SCHEMBL70035 | 0.72 | KDM4E (0.59) | HCAR2KDM4ENAPRTALDH1A1ALOX15 | |
| SCHEMBL29930363 | 0.70 | POLB (0.50) | HCAR2KDM4ENAPRTALDH1A1P4HTM | |
| SCHEMBL89539 | 0.70 | POLB (0.50) | HCAR2KDM4ENAPRTALDH1A1P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9598419-B1 | Imidazotriazine and imidazodiazine compounds | UNIVERSITE DE MONTREAL (CA) | 2017-03-21 | — | — | US | disclosed |
| US-9598419-B1 | Imidazotriazine and imidazodiazine compounds | UNIVERSITE DE MONTREAL (CA) | 2017-03-21 | — | — | US | disclosed |