Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.50 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18645026 | 0.95 | NR5A2 (0.55) | NAAAL3MBTL1SMN1; SMN2LMNANR5A2 | |
| SCHEMBL18646131 | 0.89 | POLB (0.46) | NAAAL3MBTL1SMN1; SMN2LMNANR5A2 | |
| SCHEMBL27447312 | 0.79 | L3MBTL1 (0.49) | NAAAL3MBTL1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL14117366 | 0.79 | SMN1; SMN2 (0.49) | NAAAL3MBTL1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL18645728 | 0.79 | NAAA (0.74) | NAAAL3MBTL1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8211224 | 0.79 | L3MBTL1 (0.68) | NAAAL3MBTL1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL19325618 | 0.78 | KDM4E (0.41) | SMN1; SMN2LMNAALDH1A1KDM4EHTT | |
| SCHEMBL14816297 | 0.77 | NAAA (0.66) | NAAAL3MBTL1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL14812246 | 0.77 | NAAA (0.66) | NAAAL3MBTL1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL14812810 | 0.77 | NAAA (0.66) | NAAAL3MBTL1SMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10980755-B2 | LRH-1 modulators | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-04-20 | — | — | US | disclosed |
| WO-2017044889-A1 | LRH-1 MODULATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10980755-B2 | LRH-1 modulators | NR1H4, NR1H2, NR1H3 | NAAA 3812/4885L3MBTL1 1591/4885SMN1; SMN2 4687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.