Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003874 | 0.88 | POLB (0.47) | SMN1; SMN2NPC1RAB9ATSHRHTT | |
| SCHEMBL27106031 | 0.81 | KDM4E (0.38) | SMN1; SMN2NPC1RAB9ATSHRHTT | |
| SCHEMBL18646127 | 0.79 | NAAA (0.54) | SMN1; SMN2NPC1RAB9ATSHRHTT | |
| SCHEMBL1005549 | 0.77 | ALDH1A1 (0.47) | SMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL18645026 | 0.77 | NR5A2 (0.55) | SMN1; SMN2NPC1RAB9ATSHRHTT | |
| SCHEMBL28472945 | 0.77 | ALDH1A1 (0.48) | SMN1; SMN2NPC1RAB9ATSHRHTT | |
| SCHEMBL13655602 | 0.77 | HTT (0.36) | SMN1; SMN2NPC1RAB9AHTTKDM4E | |
| SCHEMBL25779498 | 0.76 | MEN1 (0.43) | SMN1; SMN2NPC1RAB9AHPGDKDM4E | |
| SCHEMBL27447312 | 0.74 | L3MBTL1 (0.49) | SMN1; SMN2TSHRHTTHPGDKDM4E | |
| SCHEMBL19222237 | 0.73 | SMN1; SMN2 (0.42) | SMN1; SMN2NPC1RAB9ATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080177102-A1 | DENDRITIC AND STAR-SHAPED CONTRAST AGENTS FOR MEDICAL DEVICES AND BIOABSORBABLE RADIOPAQUE BULK MATERIAL AND METHOD FOR PRODUCING SAME | CORDIS US CORP | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080177102-A1 | DENDRITIC AND STAR-SHAPED CONTRAST AGENTS FOR MEDICAL DEVICES AND BIOABSORBABLE RADIOPAQUE BULK MATERIAL AND METHOD FOR PRODUCING SAME | MSR1, MYD88, CD209 | SMN1; SMN2 4093/4885NPC1 1582/4885RAB9A 504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.