Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | TPH1 | P17752 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18603450 | 0.83 | FPR2 (0.51) | LDHAPPARGPPARAKMT2AFPR2 | |
| SCHEMBL30439386 | 0.81 | SLC7A5 (0.61) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL22880668 | 0.81 | KMT2A (0.49) | LDHAPPARGPPARAKMT2AFPR2 | |
| SCHEMBL18180135 | 0.81 | CIT (0.52) | LDHAPPARGPPARAALPIPKM | |
| SCHEMBL16669866 | 0.81 | CIT (0.52) | LDHAPPARGPPARAALPIPKM | |
| SCHEMBL16669867 | 0.81 | CIT (0.52) | LDHAPPARGPPARAALPIPKM | |
| SCHEMBL30659096 | 0.81 | CIT (0.52) | LDHAPPARGPPARAALPIPKM | |
| SCHEMBL7418449 | 0.80 | ALPI (0.50) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL8628526 | 0.80 | ALPI (0.50) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL14493013 | 0.80 | ITGB3 (0.60) | LDHAPPARGPPARAACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017044584-A1 | PSMA-TARGETED NIR DYES AND THEIR USES | On Target Laboratories, LLC (US) | 2017-03-16 | — | — | WO | disclosed |