Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | FPR2 | P25090 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18588860 | 0.90 | PPARG (0.43) | PPARGPPARAMMP2MMP9 | |
| SCHEMBL18603450 | 0.88 | FPR2 (0.51) | KMT2AFPR2PPARGPPARALDHA | |
| SCHEMBL18647235 | 0.81 | LDHA (0.51) | KMT2AFPR2PPARGPPARALDHA | |
| SCHEMBL30688463 | 0.78 | MMP9 (0.48) | KMT2AMMP2MMP9 | |
| SCHEMBL10441796 | 0.76 | ITGB3 (0.60) | KMT2AFPR2PPARGPPARALDHA | |
| SCHEMBL2494620 | 0.76 | ITGB3 (0.60) | KMT2AFPR2PPARGPPARALDHA | |
| SCHEMBL18435372 | 0.76 | NPC1 (0.56) | KMT2AATM | |
| SCHEMBL14493013 | 0.76 | ITGB3 (0.60) | KMT2AFPR2PPARGPPARALDHA | |
| SCHEMBL18435195 | 0.76 | MMP9 (0.62) | MMP3MMP9 | |
| SCHEMBL16252286 | 0.76 | MMP9 (0.62) | MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3347019-B1 | PSMA-TARGETED NIR DYES AND THEIR USES | ON TARGET LABORATORIES LLC (US) | 2021-01-13 | — | — | EP | disclosed |