SCHEMBL18647883

SCHEMBL18647883

CCCCCCC(C)c1nnn[nH]1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.44
OPRM1 P35372 1/20 0.34
SPHK1 Q9NYA1 1/20 0.33
LMNA P02545 1/20 0.32
ADH1B P00325 1/20 0.32
ADH1C P00326 1/20 0.32
ADH1A P07327 1/20 0.32
ADH4 P08319 1/20 0.32
ADH7 P40394 1/20 0.32
DNM1 Q05193 2/20 0.31
ACE2 Q9BYF1 1/20 0.31
TRPM8 Q7Z2W7 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20936521 1.00 GPR84 (0.44) GPR84OPRM1SPHK1LMNAADH1B
SCHEMBL20936415 1.00 GPR84 (0.44) GPR84OPRM1SPHK1LMNAADH1B
SCHEMBL20915296 1.00 GPR84 (0.44) GPR84OPRM1SPHK1LMNAADH1B
SCHEMBL20915249 1.00 GPR84 (0.44) GPR84OPRM1SPHK1LMNAADH1B
SCHEMBL20915547 1.00 GPR84 (0.44) GPR84OPRM1SPHK1LMNAADH1B
SCHEMBL20915527 1.00 GPR84 (0.44) GPR84OPRM1SPHK1LMNAADH1B
Acetic Acid SCHEMBL9277685 0.91 GPR84 (0.45) GPR84ACE2
SCHEMBL13349287 0.84
SCHEMBL6509578 0.83 MAPT (0.37) GPR84LMNAADH1BADH1CADH1A
SCHEMBL18649822 0.83 LMNA (0.33) GPR84OPRM1LMNADNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11370762-B2 Vinylarene derivative and application SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) 2022-06-28 US disclosed
US-9598367-B2 Heterocyclic compounds as bromodomain inhibitors ZENITH EPIGENETICS LTD. (CA) 2017-03-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11370762-B2 Vinylarene derivative and application IDO1, IDO2, INMT GPR84 1929/4885OPRM1 1749/4885SPHK1 2207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.