Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 13/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | CTSE | P14091 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.33 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.33 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1864803 | 1.00 | MASP2 (0.40) | MASP2RENCTSDCTSECHRNA7 | |
| SCHEMBL1864797 | 1.00 | MASP2 (0.40) | MASP2RENCTSDCTSECHRNA7 | |
| SCHEMBL1868978 | 0.84 | MASP2 (0.44) | MASP2RENCTSDCTSECHRNA7 | |
| SCHEMBL1867873 | 0.83 | MASP2 (0.45) | MASP2RENCTSECHRNA7METTL3 | |
| Trifluoroacetic Acid SCHEMBL1873628 | 0.80 | MASP2 (0.43) | MASP2RENCHRNA7METTL3METTL14 | |
| SCHEMBL1869261 | 0.79 | MME (0.38) | MASP2RENCHRNA7METTL3METTL14 | |
| SCHEMBL1869265 | 0.79 | MME (0.38) | MASP2RENCHRNA7METTL3METTL14 | |
| SCHEMBL1869264 | 0.79 | MME (0.38) | MASP2RENCHRNA7METTL3METTL14 | |
| SCHEMBL1870522 | 0.73 | MASP2 (0.45) | MASP2CHRNA7METTL3METTL14KLKB1 | |
| SCHEMBL1874087 | 0.72 | MASP2 (0.47) | MASP2CHRNA7METTL3METTL14KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051672-A1 | AZAINDOLE DERIVATIVES | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |