Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 9/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 3/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 4/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.36 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1888157 | 0.95 | MASP2 (0.43) | MASP2KLKB1ACKR3CHRNA7KLK1 | |
| SCHEMBL1863774 | 0.87 | MASP2 (0.45) | MASP2KLKB1ACKR3CHRNA7KLK1 | |
| SCHEMBL1871998 | 0.87 | MASP2 (0.45) | MASP2KLKB1ACKR3CHRNA7KLK1 | |
| SCHEMBL1865375 | 0.87 | MASP2 (0.45) | MASP2KLKB1ACKR3CHRNA7KLK1 | |
| SCHEMBL1874220 | 0.85 | MASP2 (0.45) | MASP2KLKB1ACKR3CHRNA7KLK1 | |
| SCHEMBL1433119 | 0.82 | MASP2 (0.41) | MASP2METTL3 | |
| SCHEMBL1875013 | 0.81 | KLKB1 (0.44) | MASP2KLKB1CHRNA7KLK1ABL1 | |
| SCHEMBL1868978 | 0.81 | MASP2 (0.44) | MASP2KLKB1CHRNA7ABL1JAK1 | |
| SCHEMBL1870902 | 0.81 | MASP2 (0.43) | MASP2KLKB1CHRNA7KLK1METTL3 | |
| SCHEMBL1867150 | 0.81 | MASP2 (0.43) | MASP2KLKB1KLK1JAK1METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051672-A1 | AZAINDOLE DERIVATIVES | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |
| WO-2011051672-A1 | AZAINDOLE DERIVATIVES | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |