SCHEMBL186492

SCHEMBL186492

CC(C)(CCCCCC(=O)CCCCCC(C)(C)C(=O)O)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACLY P53396 1/20 0.61
ACACB O00763 1/20 0.59
ACACA Q13085 1/20 0.59
MAPT P10636 1/20 0.45
KMT2A Q03164 1/20 0.45
TBXAS1 P24557 2/20 0.45
TDP1 Q9NUW8 2/20 0.41
FFAR1 O14842 1/20 0.41
CPT2 P23786 1/20 0.41
PPARA Q07869 4/20 0.39
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37
LTB4R Q15722 3/20 0.37
TSHR P16473 2/20 0.37
TTR P02766 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C8 P10632 1/20 0.37
CHRM1 P11229 1/20 0.37
CYP2C9 P11712 1/20 0.37
ADRA1A P35348 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3279650 1.00 ACLY (0.61) ACLYACACBACACAMAPTKMT2A
SCHEMBL3291351 1.00 ACLY (0.61) ACLYACACBACACAMAPTKMT2A
SCHEMBL3286285 1.00 ACLY (0.61) ACLYACACBACACAMAPTKMT2A
SCHEMBL3281521 0.98 ACLY (0.57) ACLYACACBACACAMAPTKMT2A
SCHEMBL209070 0.95 ACLY (0.55) ACLYACACBACACAMAPTKMT2A
SCHEMBL13302051 0.94 ACLY (0.55) ACLYACACBACACAMAPTKMT2A
SCHEMBL16375048 0.92 ACLY (0.53) ACLYACACBACACAMAPTKMT2A
SCHEMBL16375055 0.92 ACLY (0.53) ACLYACACBACACAMAPTKMT2A
SCHEMBL187235 0.92 KMT2A (0.53) ACLYACACBACACAMAPTKMT2A
SCHEMBL13302052 0.92 ACLY (0.53) ACLYACACBACACAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114907204-B Synthesis method of bevacizidine acid 苏州特瑞药业股份有限公司 2024-08-16 CN claimed
WO-2023187833-A1 A NOVEL SALT OF BEMPEDOIC ACID ENALTEC LABS PRIVATE LIMITED (IN) 2023-10-05 WO claimed
CN-114436821-A Crystallization method of pipadiric acid intermediate 甘李药业股份有限公司 2022-05-06 CN claimed
CN-111170855-A Compound and method for synthesizing 8-hydroxy-2, 2,14, 14-tetramethylpentadecanedioic acid by using same 奥锐特药业(天津)有限公司 2020-05-19 CN claimed
EP-1564200-A1 Ketone compounds and compositions for cholesterol management and related uses Esperion Therapeutics Inc. (US) 2005-08-17 EP claimed
US-6699910-B2 TREATING AND PREVENTING CARDIOVASCULAR DISEASES, DYSLIPIDEMIAS, AND GLUCOSE METABOLISM AS HYPOGLYCEMIC AGENTS, USE TO REDUCE THE FAT CONTENT OF MEAT IN LIVESTOCK AND REDUCE THE CHOLESTEROL CONTENT OF EGGS ESPERION THERAPEUTICS, INC. 2004-03-02 US claimed
EP-1326822-A2 KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES Esperion Therapeutics Inc. (US) 2003-07-16 EP claimed
US-20030078239-A1 Ketone compounds and compositions for cholesterol management and related uses ESPERION THERAPEUTICS, INC. 2003-04-24 US claimed
WO-2002030860-A9 KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES ESPERION THERAPEUTICS INC (US) 2003-02-20 WO claimed
WO-2002030860-A2 KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES ESPERION THERAPEUTICS, INC. (US) 2002-04-18 WO claimed
CN-116924886-B Synthesis method of 8-oxo-2,2,14,14-tetramethyl pentadecanedioic acid 武汉武药科技有限公司 2025-08-29 CN disclosed
WO-2025092475-A1 SYNTHESIS METHOD FOR BEMPEDOIC ACID AND BEMPEDOIC ACID INTERMEDIATE, AND BEMPEDOIC ACID INTERMEDIATE 扬州奥锐特药业有限公司 2025-05-08 WO disclosed
CN-119930422-A Preparation method of bevacizidine acid and intermediate thereof 扬州奥锐特药业有限公司 2025-05-06 CN disclosed
CN-119161243-A Preparation method of bevacizidine acid 山西库邦生物医药科技有限公司 2024-12-20 CN disclosed
CN-114907204-B Synthesis method of bevacizidine acid 苏州特瑞药业股份有限公司 2024-08-16 CN disclosed
WO-2004067489-A2 HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES ESPERION THERAPEUTICS, INC. (US) 2004-08-12 WO disclosed
US-6699910-B2 TREATING AND PREVENTING CARDIOVASCULAR DISEASES, DYSLIPIDEMIAS, AND GLUCOSE METABOLISM AS HYPOGLYCEMIC AGENTS, USE TO REDUCE THE FAT CONTENT OF MEAT IN LIVESTOCK AND REDUCE THE CHOLESTEROL CONTENT OF EGGS ESPERION THERAPEUTICS, INC. 2004-03-02 US disclosed
EP-1326822-A2 KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES Esperion Therapeutics Inc. (US) 2003-07-16 EP disclosed
WO-2002030860-A9 KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES ESPERION THERAPEUTICS INC (US) 2003-02-20 WO disclosed
WO-2002030860-A2 KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES ESPERION THERAPEUTICS, INC. (US) 2002-04-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030078239-A1 Ketone compounds and compositions for cholesterol management and related uses PC, HMGCR, GPR119 ACLY 358/4885ACACB 91/4885ACACA 38/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.