SCHEMBL1864976

SCHEMBL1864976

CCCCCCCC/C=C\CCCCCCCCCCCC(=O)N(CC(N)=O)C(=O)CCCCCCCCCCC/C=C\CCCCCCCC

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.69
SOAT1 P35610 2/20 0.69
CYP1A2 P05177 2/20 0.69
CYP2C19 P33261 2/20 0.69
KMT2A Q03164 2/20 0.69
MEN1 O00255 1/20 0.69
TP53 P04637 1/20 0.69
CYP3A4 P08684 1/20 0.69
KDM4E B2RXH2 2/20 0.63
CNR1 P21554 1/20 0.56
TERT O14746 3/20 0.54
PTPN1 P18031 3/20 0.54
PPARG P37231 3/20 0.54
PPARD Q03181 3/20 0.54
PPARA Q07869 3/20 0.54
MAPT P10636 2/20 0.54
BLM P54132 2/20 0.54
HSD17B10 Q99714 2/20 0.54
FABP4 P15090 2/20 0.54
GMNN O75496 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2335481 1.00 FAAH (0.69) FAAHSOAT1CYP1A2CYP2C19KMT2A
SCHEMBL29422232 0.90 SOAT1 (0.50) FAAHSOAT1CYP1A2CYP2C19KMT2A
SCHEMBL5574516 0.90 SOAT1 (0.50) FAAHSOAT1CYP1A2CYP2C19KMT2A
SCHEMBL28984571 0.90 SOAT1 (0.50) FAAHSOAT1CYP1A2CYP2C19KMT2A
SCHEMBL2428089 0.90 SOAT1 (0.50) FAAHSOAT1CYP1A2CYP2C19KMT2A
SCHEMBL3629441 0.83 FAAH (0.79) FAAHSOAT1CYP1A2CYP2C19KMT2A
SCHEMBL3629436 0.83 FAAH (0.79) FAAHSOAT1CYP1A2CYP2C19KMT2A
SCHEMBL5706363 0.83 FAAH (0.79) FAAHSOAT1CYP1A2CYP2C19KMT2A
SCHEMBL19668673 0.83 TERT (0.61) FAAHSOAT1CYP1A2CYP2C19KMT2A
SCHEMBL28206503 0.83 TERT (0.61) FAAHSOAT1CYP1A2CYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110223257-A1 RELEASABLE FUSOGENIC LIPIDS FOR NUCLEIC ACIDS DELIVERY SYSTEMS ENZON PHARMACEUTICALS, INC. (US) 2011-09-15 US disclosed
EP-2362728-A1 RELEASABLE POLYMERIC LIPIDS FOR NUCLEIC ACIDS DELIVERY SYSTEM Enzon Pharmaceuticals, Inc. (US) 2011-09-07 EP disclosed
EP-2355799-A1 RELEASABLE FUSOGENIC LIPIDS FOR NUCLEIC ACIDS DELIVERY SYSTEMS Enzon Pharmaceuticals, Inc. (US) 2011-08-17 EP disclosed
WO-2010057160-A9 RELEASABLE FUSOGENIC LIPIDS FOR NUCLEIC ACIDS DELIVERY SYSTEMS ENZON PHARMACEUTICALS, INC. (US) 2011-05-05 WO disclosed
WO-2010057150-A1 RELEASABLE POLYMERIC LIPIDS FOR NUCLEIC ACIDS DELIVERY SYSTEMS ENZON PHARMACEUTICALS, INC. (US) 2010-05-20 WO disclosed
WO-2010057160-A1 RELEASABLE FUSOGENIC LIPIDS FOR NUCLEIC ACIDS DELIVERY SYSTEMS ENZON PHARMACEUTICALS, INC. (US) 2010-05-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110223257-A1 RELEASABLE FUSOGENIC LIPIDS FOR NUCLEIC ACIDS DELIVERY SYSTEMS FUS, HNRNPUL2, HNRNPDL FAAH 1534/4885SOAT1 282/4885CYP1A2 4878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.