Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.45 |
| ▸ | PPARG | P37231 | 6/20 | 0.45 |
| ▸ | PPARD | Q03181 | 6/20 | 0.45 |
| ▸ | PPARA | Q07869 | 6/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29422232 | 1.00 | SOAT1 (0.50) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL2428089 | 1.00 | SOAT1 (0.50) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL28984571 | 1.00 | SOAT1 (0.50) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL1864976 | 0.90 | FAAH (0.69) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL2335481 | 0.90 | FAAH (0.69) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL29637717 | 0.87 | GPR84 (0.50) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL28925137 | 0.82 | SOAT1 (0.48) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL17272316 | 0.82 | GPR84 (0.58) | MEN1KMT2AGPR84PPARGPPARD | |
| SCHEMBL29037394 | 0.82 | GPR84 (0.58) | MEN1KMT2AGPR84PPARGPPARD | |
| SCHEMBL2052582 | 0.82 | GPR84 (0.58) | MEN1KMT2AGPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122055374-A | Lipid compounds and compositions for tissue-specific delivery of active substances | 韩国生命工学研究院 | 2026-05-15 | — | — | CN | claimed |
| CN-115957187-A | Lipid nanoparticle composition and drug delivery system prepared from same | 北京启辰生生物科技有限公司 | 2023-04-14 | — | — | CN | claimed |
| CN-115960180-A | 2019-nCoV S protein mutant and genetically engineered mRNA and vaccine composition thereof | 北京启辰生生物科技有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-115745788-A | Ionizable lipid compound and preparation method and application thereof | 国家纳米科学中心 | 2023-03-07 | — | — | CN | disclosed |
| CN-115484932-A | Compositions and methods for targeted RNA delivery | 维乎医疗有限公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-115074343-A | CAS transgenic mouse embryonic stem cell, mouse and application thereof | 瑞泽恩制药公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-111163633-B | Non-human animals comprising humanized TTR loci and methods of use thereof | 瑞泽恩制药公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-114746125-A | CRISPR and AAV strategies for X-linked juvenile retinoschisis therapy | 瑞泽恩制药公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114616002-A | Transcriptional regulation in animals using CRISPR/CAS systems delivered by lipid nanoparticles | 瑞泽恩制药公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-110891420-B | CAS transgenic mouse embryonic stem cell, mouse and application thereof | 瑞泽恩制药公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-114206108-A | Non-human animals comprising a humanized coagulation factor 12 locus | 瑞泽恩制药公司 | 2022-03-18 | — | — | CN | disclosed |
| US-20040209366-A1 | Methods for attaching proteins to lipidic microparticles with high efficiency | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-10-21 | — | — | US | disclosed |
| US-6803053-B2 | CONDENSED NUCLEIC ACID/LIPID COMPLEX FOR INCREASING SHELF LIFE AND HIGH TRANSFECTION ACTIVITY IN VIVO FOLLOWING INTRAVENOUS INJECTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-10-12 | — | — | US | disclosed |
| US-6528087-B2 | Increasing the shelf life of a lipid: nucleic acid complex by contacting a nucleic acid with an organic polycation such as spermine to produce a condensed nucleic acid, and combining with an amphiphilic cationic lipid to complex | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-03-04 | — | — | US | disclosed |
| US-20030003143-A1 | Lipidic microparticles linked to multiple proteins | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-01-02 | — | — | US | disclosed |
| EP-1078079-A4 | METHODS OF FORMING PROTEIN-LINKED LIPIDIC MICROPARTICLES, AND COMPOSITIONS THEREOF | UNIV CALIFORNIA (US) | 2002-03-13 | — | — | EP | disclosed |
| US-20020001612-A1 | Methods of forming protein-linked lipidic microparticles, and compositions thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-01-03 | — | — | US | disclosed |
| US-6210707-B1 | LIPID:NUCLEIC ACID COMPLEXES THAT HAVE INCREASED SHELF LIFE AND HIGH TRANSFECTION ACTIVITY IN VIVO | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-04-03 | — | — | US | disclosed |
| EP-1078079-A1 | METHODS OF FORMING PROTEIN-LINKED LIPIDIC MICROPARTICLES, AND COMPOSITIONS THEREOF | The Regents of the University of California (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058694-A1 | METHODS OF FORMING PROTEIN-LINKED LIPIDIC MICROPARTICLES, AND COMPOSITIONS THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-11-18 | — | — | WO | disclosed |