Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.51 |
| ▸ | DRD3 | P35462 | 4/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2940793 | 0.85 | MEN1 (0.49) | ALDH1A1LMNAKMT2AMAPTMAPK1 | |
| SCHEMBL27664430 | 0.83 | MEN1 (0.51) | ALDH1A1LMNAKMT2AMAPTMAPK1 | |
| SCHEMBL1308333 | 0.82 | ADRA2C (0.60) | DRD2DRD3ADRA2CDRD4HTR2A | |
| SCHEMBL13243993 | 0.81 | ADRB1 (0.65) | DRD2DRD3ADRA2CALDH1A1LMNA | |
| SCHEMBL24309229 | 0.80 | DRD2 (0.69) | DRD2DRD3ADRA2CDRD4HTR2A | |
| SCHEMBL3626941 | 0.80 | ADRB1 (0.69) | DRD2DRD3ALDH1A1HTR2AHTR1A | |
| SCHEMBL24309751 | 0.80 | DRD2 (0.50) | DRD2DRD3ADRA2CALDH1A1DRD4 | |
| SCHEMBL11094567 | 0.80 | HSD17B10 (0.46) | ALDH1A1LMNAKMT2AMAPTADRB1 | |
| SCHEMBL12359055 | 0.78 | DRD2 (0.71) | DRD2DRD3ADRA2CDRD4HTR2A | |
| SCHEMBL3595699 | 0.78 | ADRA2C (0.55) | DRD2DRD3ADRA2CALDH1A1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006803-A9 | 3-0X0-2, 3, -DIHYDRO-1H-ISOINDOLE-4-CARBOXAMIDES WITH SELECTIVE PARP-1 INHIBITION | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2011-05-05 | — | — | WO | disclosed |