Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1989624 | 0.81 | EPHX2 (0.46) | HPGDHTTP2RX7 | |
| SCHEMBL4269892 | 0.79 | TSHR (0.54) | ROCK2ROCK1NPC1TSHRHPGD | |
| SCHEMBL1865359 | 0.79 | TSHR (0.49) | ROCK2ROCK1NPC1TSHRHPGD | |
| SCHEMBL1869075 | 0.79 | HPGD (0.52) | ROCK2ROCK1NPC1TSHRHPGD | |
| SCHEMBL1873656 | 0.77 | HTT (0.54) | ROCK2ROCK1TSHRHPGDHTT | |
| SCHEMBL1991831 | 0.76 | SETDB1 (0.52) | ROCK2ROCK1NPC1TSHRHPGD | |
| SCHEMBL1866652 | 0.76 | ALDH1A1 (0.52) | ROCK2ROCK1NPC1TSHRHPGD | |
| SCHEMBL1866044 | 0.75 | LMNA (0.42) | ROCK2ROCK1TSHRLMNATP53 | |
| SCHEMBL16899272 | 0.74 | HTT (0.48) | ROCK2ROCK1NPC1TSHRHTT | |
| SCHEMBL5177742 | 0.74 | PYCR1 (0.42) | OPRM1TSHRHPGDLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152332-A1 | Pesticidal Heterocyclic Compounds | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
| WO-2011051455-A1 | PESTICIDAL HETEROCYCLIC COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152332-A1 | Pesticidal Heterocyclic Compounds | DDT, PTMS, CYP4X1 | OPRM1 2177/4885ROCK2 924/4885ROCK1 503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.