Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4123220 | 0.92 | CA1 (0.48) | MEN1KMT2APOLBTDP1CA2 | |
| SCHEMBL29222155 | 0.92 | CA1 (0.48) | MEN1KMT2APOLBTDP1CA2 | |
| SCHEMBL6418180 | 0.84 | MEN1 (0.49) | MEN1KMT2APOLBTDP1SMN1; SMN2 | |
| SCHEMBL6418177 | 0.84 | MEN1 (0.49) | MEN1KMT2APOLBTDP1SMN1; SMN2 | |
| SCHEMBL28045965 | 0.83 | KDM4E (0.61) | MEN1KMT2APOLBTDP1CA2 | |
| SCHEMBL27900148 | 0.82 | MEN1 (0.53) | MEN1KMT2AKDM4ERECQLSMN1; SMN2 | |
| SCHEMBL4966206 | 0.82 | ALDH1A1 (0.66) | MEN1KMT2APOLBKDM4ERECQL | |
| SCHEMBL27917822 | 0.82 | HTT (0.62) | MEN1KMT2AKDM4ERECQLSMN1; SMN2 | |
| Bicarbonate SCHEMBL15226074 | 0.82 | SMN1; SMN2 (0.63) | MEN1KMT2AKDM4ERECQLSMN1; SMN2 | |
| SCHEMBL3668793 | 0.82 | CA1 (0.51) | MEN1KMT2APOLBTDP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060321-A1 | TRANSGLUTAMINASE TG2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | CHDI, INC. (US) | 2011-05-19 | — | — | WO | disclosed |