Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 3/20 | 0.55 |
| ▸ | HTR7 | P34969 | 3/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4966206 | 0.86 | ALDH1A1 (0.66) | HTTMEN1KMT2AKDM4ERECQL | |
| SCHEMBL27900148 | 0.86 | MEN1 (0.53) | HTTMEN1KMT2AKDM4ERECQL | |
| SCHEMBL28802144 | 0.84 | HTR1A (0.59) | HTTHTR1AHTR7SFRP1HDAC8 | |
| SCHEMBL3660279 | 0.83 | ALDH1A1 (0.66) | HTTHTR1AHTR7EPHX2MEN1 | |
| SCHEMBL28822460 | 0.82 | KIT (0.51) | HTTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1865107 | 0.82 | MEN1 (0.48) | EPHX2MEN1KMT2AKDM4ERECQL | |
| SCHEMBL4737973 | 0.81 | HDAC8 (0.53) | HTTHTR1AHTR7EPHX2KDM4E | |
| SCHEMBL2178427 | 0.81 | KDM4E (0.68) | HTTHTR1AHTR7KMT2AKDM4E | |
| SCHEMBL7533683 | 0.81 | STS (0.73) | HTTSFRP1ALDH1A1STS | |
| SCHEMBL28805541 | 0.81 | STS (0.70) | HTTMEN1KMT2AALDH1A1STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068797-A | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | SANOFI SA | 2013-04-24 | — | — | CN | disclosed |