Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27411577 | 0.84 | CYP3A4 (0.39) | LMNA | |
| SCHEMBL18651724 | 0.82 | LMNA (0.38) | LMNAMAOAPTGS1TSHR | |
| SCHEMBL12172005 | 0.78 | LMNA (0.43) | LMNAMAOAPTGS1 | |
| SCHEMBL12172084 | 0.77 | LMNA (0.41) | LMNAMAOAPTGS1MTNR1AMTNR1B | |
| SCHEMBL14587067 | 0.77 | LMNA (0.52) | LMNAMAOAPTGS1MTNR1AMTNR1B | |
| SCHEMBL10013740 | 0.77 | LMNA (0.61) | LMNAMAOAPTGS1MTNR1AMTNR1B | |
| SCHEMBL4596021 | 0.76 | LMNA (0.47) | LMNAMAOAPTGS1 | |
| SCHEMBL17395999 | 0.75 | LMNA (0.50) | LMNAMAOAPTGS1MTNR1AMTNR1B | |
| SCHEMBL14265620 | 0.75 | LTA4H (0.46) | — | |
| SCHEMBL6273665 | 0.74 | LMNA (0.48) | LMNAMAOAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170080397-A1 | DISPERSANT, DISPERSION COMPOSITION, AND FIBROUS SHEET | MEISEI CHEMICAL WORKS, LTD. (JP) | 2017-03-23 | — | — | US | disclosed |