SCHEMBL12172005

SCHEMBL12172005

COCCOCC(COc1ccccc1)OCCOC

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.43
▸ MAOA P21397 1/20 0.40
▸ PTGS1 P23219 1/20 0.40
▸ SCN4A P35499 2/20 0.39
▸ LTA4H P09960 1/20 0.39
▸ PLA2G2A P14555 8/20 0.38
▸ KCNA3 P22001 1/20 0.38
▸ PLA2G10 O15496 3/20 0.38
▸ PLA2G1B P04054 2/20 0.38
▸ PLA2G5 P39877 2/20 0.38
▸ PKM P14618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27254126 0.93 LMNA (0.48) LMNAMAOAPTGS1SCN4AKCNA3
SCHEMBL12978498 0.87 LMNA (0.45) LMNA
SCHEMBL13085598 0.86 LMNA (0.37) LMNAMAOAPTGS1SCN4ALTA4H
SCHEMBL27438647 0.83 LMNA (0.36) LMNAMAOAPTGS1SCN4ALTA4H
SCHEMBL12098568 0.83 ALDH1A1 (0.50) LMNAMAOAPTGS1SCN4APLA2G2A
SCHEMBL26802641 0.81 ALDH1A1 (0.40) LMNALTA4HPLA2G2APLA2G10PLA2G1B
SCHEMBL6882239 0.81 MTNR1A (0.48) LMNA
SCHEMBL10038814 0.81 TSHR (0.44) PLA2G2APLA2G10
SCHEMBL27250609 0.80 MAPK1 (0.43) LMNA
SCHEMBL21398845 0.79 TSHR (0.42) PLA2G2APLA2G10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120232169-A1 HIGHLY MONODISPERSE BRANCHED PEG-LIPID CONJUGATES BIOZONE PHARMACEUTICALS, INC. (US) 2012-09-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120232169-A1 HIGHLY MONODISPERSE BRANCHED PEG-LIPID CONJUGATES LIPA, CETP, DGAT2 LMNA 3678/4885MAOA 4163/4885PTGS1 1911/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback