Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1177836 | 0.90 | ALDH1A1 (0.73) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A | |
| SCHEMBL21861568 | 0.89 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A | |
| SCHEMBL31634981 | 0.86 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A | |
| SCHEMBL13451270 | 0.86 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A | |
| SCHEMBL7632247 | 0.85 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A | |
| Succinic Acid Monobenzyl Ester SCHEMBL827012 | 0.85 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A | |
| Succinic Acid SCHEMBL28290797 | 0.85 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A | |
| SCHEMBL1856208 | 0.85 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A | |
| SCHEMBL6381740 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A | |
| SCHEMBL27494446 | 0.83 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943751-B2 | Ladder copolymers | NEW YORK UNIVERSITY (US) | 2011-05-17 | — | — | US | disclosed |
| US-20090137738-A1 | LADDER COPOLYMERS | NEW YORK UNIVERSITY (US) | 2009-05-28 | — | — | US | disclosed |
| US-7479548-B1 | Nucleic acid based ladder copolymers | NEW YORK UNIVERSITY (US) | 2009-01-20 | — | — | US | disclosed |
| US-20090005329-A1 | NUCLEIC ACID BASED LADDER COPOLYMERS | NEW YORK UNIVERSITY (US) | 2009-01-01 | — | — | US | disclosed |
| EP-1639078-A2 | LADDER COPOLYMERS | New York University (US) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005001035-A2 | LADDER COPOLYMERS | NEW YORK UNIVERSITY (US) | 2005-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005329-A1 | NUCLEIC ACID BASED LADDER COPOLYMERS | POLL, POLM, POLRMT | ALDH1A1 2760/4885MAPK1 1047/4885L3MBTL1 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.