Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 6/20 | 0.80 |
| ▸ | ESR1 | P03372 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | XDH | P47989 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773961 | 0.89 | SERPINE1 (1.00) | SERPINE1ESR1L3MBTL1KDM4ELMNA | |
| SCHEMBL23484199 | 0.89 | SERPINE1 (0.80) | SERPINE1ESR1L3MBTL1KDM4ELMNA | |
| SCHEMBL18650105 | 0.87 | SERPINE1 (0.62) | SERPINE1ESR1L3MBTL1KDM4ELMNA | |
| SCHEMBL23484207 | 0.85 | SERPINE1 (0.73) | SERPINE1ESR1L3MBTL1KDM4ELMNA | |
| SCHEMBL27255661 | 0.84 | ESR1 (0.58) | SERPINE1ESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL13286811 | 0.83 | SERPINE1 (0.87) | SERPINE1ESR1L3MBTL1KDM4ELMNA | |
| SCHEMBL18652191 | 0.82 | CA12 (0.67) | SERPINE1ESR1L3MBTL1KDM4EPOLB | |
| SCHEMBL21234569 | 0.82 | SERPINE1 (0.70) | SERPINE1ESR1L3MBTL1KDM4ELMNA | |
| SCHEMBL18746620 | 0.82 | SERPINE1 (0.70) | SERPINE1ESR1L3MBTL1KDM4ELMNA | |
| SCHEMBL24871963 | 0.80 | SERPINE1 (0.67) | SERPINE1ESR1L3MBTL1TDP1TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111560180-B | Composition, cured product and article | 荒川化学工业株式会社 | 2022-07-05 | — | — | CN | disclosed |
| CN-111560180-A | Composition, cured product and article | 荒川化学工业株式会社 | 2020-08-21 | — | — | CN | disclosed |
| US-20170081346-A1 | MESOSCOPIC MATERIALS COMPRISED OF ORDERED SUPERLATTICES OF MICROPOROUS METAL-ORGANIC FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170081346-A1 | MESOSCOPIC MATERIALS COMPRISED OF ORDERED SUPERLATTICES OF MICROPOROUS METAL-ORGANIC FRAMEWORKS | MCM2, YTHDF2, MCM6 | SERPINE1 2260/4885ESR1 3895/4885L3MBTL1 593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.