SCHEMBL186536

SCHEMBL186536

Cc1ccccc1N(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
ACHE P22303 3/20 0.43
ALDH1A1 P00352 4/20 0.41
CYP3A4 P08684 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
MAPT P10636 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
LMNA P02545 3/20 0.38
TRPM8 Q7Z2W7 1/20 0.38
HDAC6 Q9UBN7 1/20 0.37
SIGMAR1 Q99720 1/20 0.36
APP P05067 1/20 0.36
MEN1 O00255 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL28302574 0.98 TSHR (0.41) TSHRACHEALDH1A1CYP3A4TDP1
SCHEMBL8943827 0.98 ALDH1A1 (0.44) TSHRACHEALDH1A1CYP3A4TDP1
SCHEMBL3513273 0.95 TSHR (0.39) TSHRACHEALDH1A1CYP3A4TDP1
SCHEMBL3477596 0.95 ALDH1A1 (0.48) TSHRACHEALDH1A1CYP3A4TDP1
SCHEMBL8470149 0.95 TSHR (0.43) TSHRACHEALDH1A1CYP3A4TDP1
SCHEMBL15247033 0.93 ALDH1A1 (0.46) TSHRACHEALDH1A1CYP3A4TDP1
SCHEMBL3370034 0.93 TSHR (0.38) TSHRACHEALDH1A1CYP3A4TDP1
SCHEMBL7149189 0.93 TSHR (0.41) TSHRACHEALDH1A1CYP3A4TDP1
SCHEMBL10053558 0.91 CYP2C19 (0.42) TSHRACHEALDH1A1CYP3A4TDP1
SCHEMBL73930 0.91 CYP3A4 (0.40) TSHRACHEALDH1A1CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 656 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116217883-A Carbon quantum dot modified fluorescent waterborne polyurethane and preparation method thereof 万华化学集团股份有限公司 2023-06-06 CN claimed
US-20140124763-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT MADE WITH THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2014-05-08 US claimed
US-8466458-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2013-06-18 US claimed
US-20110114930-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG MOBILE DISPLAY CO., LTD., (KR) 2011-05-19 US claimed
CN-1887860-A Second-order non-linear optical chromophore containing trianilino group and its synthesis process UNIV ZHEJIANG (CN) 2007-01-03 CN claimed
US-6558624-B1 Sensitive spectroscopic detection of adsorbed small scale samples GENERAL ELECTRIC COMPANY 2003-05-06 US claimed
WO-2002008731-A1 METHOD AND ANALYTICAL SYSTEM FOR RAPID SCREENING OF COMBINATORIAL LIBRARIES GENERAL ELECTRIC COMPANY A CORPORATION OF THE STATE OF NEW YORK (US) 2002-01-31 WO claimed
US-6433115-B1 None US disclosed
US-20250333380-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME IDEMITSU KOSAN CO.,LTD. (JP) 2025-10-30 US disclosed
US-20250186593-A1 TARGETED DELIVERY TO BETA CELLS THE BROAD INSTITUTE, INC. 2025-06-12 US disclosed
US-12232414-B2 Aromatic amine derivatives and organic electroluminescent elements using same IDEMITSU KOSAN CO., LTD. (JP) 2025-02-18 US disclosed
US-12208140-B2 Targeted delivery to beta cells THE BROAD INSTITUTE, INC. (US) 2025-01-28 US disclosed
US-20240334821-A1 Electroluminescent Device UDC IRELAND LTD (IE) 2024-10-03 US disclosed
US-5196592-A Rhodium containing dehydrogenation catalyst BAYER AKTIENGESELLSCHAFT (DE) 1993-03-23 US disclosed
US-5116708-A HOLE TRANSPORTING MATERIAL NIPPON OIL COMPANY, LIMITED (JP) 1992-05-26 US disclosed
EP-0372979-A2 Hole transporting material NIPPON OIL COMPANY, LIMITED (JP) 1990-06-13 EP disclosed
EP-0014061-B1 PHOTOSENSITIVE IMAGING MEMBER AND METHOD XEROX CORPORATION (US) 1983-04-06 EP disclosed
US-4316783-A CROSSLINKING, IRRADIATION JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 1982-02-23 US disclosed
EP-0014061-A1 Photosensitive imaging member and method XEROX CORPORATION (US) 1980-08-06 EP disclosed
US-4139390-A Presensitized printing plate having a print-out image EASTMAN KODAK COMPANY (US) 1979-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240334821-A1 Electroluminescent Device PNPO, ODC1, AXL TSHR 2334/4885ACHE 183/4885ALDH1A1 436/4885
US-20250333380-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME ARSA, AHR, AOC2 TSHR 1928/4885ACHE 2405/4885ALDH1A1 292/4885
US-12208140-B2 Targeted delivery to beta cells IAPP, ZFR, ZC3H11A TSHR 3001/4885ACHE 3874/4885ALDH1A1 3259/4885
US-20250186593-A1 TARGETED DELIVERY TO BETA CELLS IAPP, ZFR, ZC3H11A TSHR 3001/4885ACHE 3874/4885ALDH1A1 3259/4885
US-12232414-B2 Aromatic amine derivatives and organic electroluminescent elements using same AOC2, AHR, AOC3 TSHR 973/4885ACHE 1979/4885ALDH1A1 717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.