SCHEMBL3370034

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL186536	0.93	TSHR (0.43)	TSHRACHECYP3A4ALDH1A1MAPT
	SCHEMBL8943827	0.91	ALDH1A1 (0.44)	TSHRACHECYP3A4ALDH1A1MAPT
	Phosphine SCHEMBL28302574	0.91	TSHR (0.41)	TSHRACHECYP3A4ALDH1A1MAPT
	SCHEMBL17734750	0.90	CYP3A4 (0.33)	TSHRACHECYP3A4ALDH1A1MAPT
	SCHEMBL12551587	0.89	TRPM8 (0.36)	TSHRCYP3A4HDAC6LMNATRPM8
	SCHEMBL3513273	0.89	TSHR (0.39)	TSHRACHECYP3A4ALDH1A1MAPT
	SCHEMBL3477596	0.89	ALDH1A1 (0.48)	TSHRACHECYP3A4ALDH1A1MAPT
	SCHEMBL29372483	0.89	ACHE (0.43)	TSHRACHECYP3A4ALDH1A1TDP1
	SCHEMBL8470149	0.89	TSHR (0.43)	TSHRACHECYP3A4ALDH1A1MAPT
	SCHEMBL312994	0.89	ACHE (0.43)	TSHRACHECYP3A4ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.