Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.53 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.45 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GLI1 | P08151 | 1/20 | 0.45 |
| ▸ | GLI2 | P10070 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15989120 | 0.82 | GPR132 (0.58) | GPR132MRGPRX4HPGD | |
| SCHEMBL18653931 | 0.80 | LNPEP (0.51) | PDE5A | |
| SCHEMBL18867826 | 0.80 | GPR132 (0.51) | GPR132MRGPRX4HPGDMAP1LC3BMAP1LC3A | |
| SCHEMBL18653960 | 0.78 | LNPEP (0.43) | HPGDMEN1KMT2ATSHR | |
| SCHEMBL16800047 | 0.77 | GPR132 (0.46) | PDE5AGPR132MRGPRX4HPGDCYP4F2 | |
| SCHEMBL16800046 | 0.77 | GPR132 (0.46) | PDE5AGPR132MRGPRX4HPGDCYP4F2 | |
| SCHEMBL16800041 | 0.76 | GPR132 (0.45) | PDE5AGPR132MRGPRX4HPGDCYP4F2 | |
| SCHEMBL16800026 | 0.76 | GPR132 (0.45) | PDE5AGPR132MRGPRX4HPGDCYP4F2 | |
| SCHEMBL16802471 | 0.76 | GPR132 (0.45) | PDE5AGPR132MRGPRX4HPGDCYP4F2 | |
| SCHEMBL16800028 | 0.76 | GPR132 (0.45) | PDE5AGPR132MRGPRX4HPGDCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2958889-B1 | NEOSEPTINS: SMALL MOLECULE ADJUVANTS | SCRIPPS RESEARCH INST (US) | 2017-03-22 | — | — | EP | disclosed |