Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ESRRB | O95718 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CCKAR | P32238 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17774895 | 0.85 | ALDH1A1 (0.44) | LNPEPALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL18653931 | 0.81 | LNPEP (0.51) | LNPEPCA2CA1 | |
| SCHEMBL17403320 | 0.81 | CCKAR (0.49) | LNPEPCCKAR | |
| SCHEMBL18653962 | 0.78 | PDE5A (0.53) | MEN1KMT2ATSHRHPGD | |
| SCHEMBL5063446 | 0.75 | KEAP1 (0.56) | ALDH1A1KDM4EGAACA2CCKAR | |
| SCHEMBL5063453 | 0.75 | KEAP1 (0.56) | ALDH1A1KDM4EGAACA2CCKAR | |
| SCHEMBL15989099 | 0.74 | LNPEP (0.47) | LNPEPMEN1KMT2AMAPT | |
| SCHEMBL26080336 | 0.72 | HRH3 (0.53) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL23440037 | 0.71 | ALDH1A1 (0.69) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL1533823 | 0.71 | ALDH1A1 (0.69) | ALDH1A1KDM4EGAAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2958889-B1 | NEOSEPTINS: SMALL MOLECULE ADJUVANTS | SCRIPPS RESEARCH INST (US) | 2017-03-22 | — | — | EP | disclosed |